Rodrigo Otávio Silveira Silva (Author), Maja Rupnik (Author), Amanda Nádia Diniz (Author), Eduardo Garcia Vilela (Author), Francisco Carlos Faria Lobato (Author)

Abstract

Clostridium difficile is an emerging enteropathogen responsible for pseudomembranous colitis in humans and diarrhoea in several domestic and wild animal species. Despite its known importance, there are few studies aboutC. difficile polymerase chain reaction (PCR) ribotypes in Brazil and the actual knowledge is restricted to studies on human isolates. The aim of the study was therefore to compare C. difficileribotypes isolated from humans and animals in Brazil. Seventy-six C. difficile strains isolated from humans (n = 25), dogs (n = 23), piglets (n = 12), foals (n = 7), calves (n = 7), one cat, and one manned wolf were distributed into 24 different PCR ribotypes. Among toxigenic strains, PCR ribotypes 014/020 and 106 were the most common, accounting for 14 (18.4%) and eight (10.5%) samples, respectively. Fourteen different PCR ribotypes were detected among human isolates, nine of them have also been identified in at least one animal species. PCR ribotype 027 was not detected, whereas 078 were found only in foals. This data suggests a high diversity of PCR ribotypes in humans and animals in Brazil and support the discussion of C. difficile as a zoonotic pathogen.

Keywords

pseudomembranous colitis;zoonosis;

Data

Language: English
Year of publishing:
Typology: 1.01 - Original Scientific Article
Organization: UM MF - Faculty of Medicine
UDC: 579.852.13
COBISS: 512578616 Link will open in a new window
ISSN: 1678-8060
Views: 988
Downloads: 352
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Other data

Secondary language: Slovenian
Secondary keywords: Clostridium difficile;
URN: URN:SI:UM:
Type (COBISS): Scientific work
Pages: str. 1062-1065
Volume: ǂVol. ǂ110
Issue: ǂiss. ǂ8
Chronology: 2015
DOI: 10.1590/0074-02760150294
ID: 9142425