Ugotavljanje antioksidativne aktivnosti izvlečkov lubja navadne jelke (Abies alba mill.) iz različnih delov Slovenije in njihovih frakcij

Povzetek

Ključne besede

Podatki

Jezik:	Slovenski jezik
Leto izida:	2015
Tipologija:	2.11 - Diplomsko delo
Organizacija:	UL FFA - Fakulteta za farmacijo
Založnik:	[M. Miklavčič]
UDK:	547.56+582.475:615.3(043.2)
COBISS:	3805553
Št. ogledov:	773
Št. prenosov:	222
Ocena:	0 (0 glasov)
Metapodatki:

Ostali podatki

Sekundarni jezik:	Angleški jezik
Sekundarni naslov:	Determination of antioxidant activity of silver fir (Abies alba mill.) bark extracts from different places in Slovenia
Sekundarni povzetek:	Radiation, pollution, metabolic processes of oxigen combustion in the human body can cause production of radicals. These molecules can lead to oxidative stress disorders, injuries and diseases. The nature has provided solution for removing radicals, preventing or curing the damage caused by radicals. Polyphenoles; flavonoids and tannins are very important antioxidants in nature. They play an important role in human diet. People with weakened immune system are advised to take purified and highly concentrated polyphenols in supplements. Pycnogenol, from the French Pinus pinaster bark, is one of the already well known and mostly used antioxidants. The white fir bark extract has also some antioxidant effect. This extract contains pycnogenol – like active substances; catechin, epicatechin, quercetin and epigallocatechine gallate. In the thesis we tested and compared white fir bark extracts from different locations in Slovenia (Celje, Dolenjske Toplice, Dolenja vas, Dragomer, Idrija, Lovrenc, Metlika, Slovenske Konjice, Snežnik, Trebnje, Trojane, Zaplana), and fractions of the extract from Kočevska Reka. We used DPPH, ABTS, superoxide and hydroxil radical scavenging methods and the reducing power determinating method. We performed tests with reagents that caused colour change of the samples and their absorbance. The latter was measured with the Tecan spectrophotometer which allows the measurement of more samples simultaneausly. The obtained results confirmed the antioxidant activity (AA) of tested silver fir extracts. The most active was the sample from Metlika. It gave the best results with NADH, was also twice second, twice third and once fourth. Tests on sample fractions showed high antioxidant activity of some fractions that were comparable with standards' AA or higher. On the other side there were fractions with low or practically no AA.
Sekundarne ključne besede:	Polifenoli;Antioksidanti;
Vrsta dela (COBISS):	Diplomsko delo
Komentar na gradivo:	Univ. v Ljubljani, Fak. za farmacijo, univerzitetni študij farmacije
Strani:	VII, 45 f.
ID:	12050933