Strategies for biofilm inhibition and virulence attenuation of foodborne pathogen-Escherichia coli O157:H7

Sandra Oloketuyi (Avtor), Fazlurrahman Khan (Avtor)

Povzetek

Enterohemorrhagic Escherichia coli (E. coli) O157:H7, a gram-negative bacteria identified as a foodborne pathogen causing severe disease is of great concern worldwide. The pathogenicity of E. coli O157:H7 is due to the presence of some virulence factors and its ability to form biofilm which resist antimicrobial compounds, withstand harsh environmental condition and protects from the host immune responses. Formation of biofilm is a multistep process such as adhesion, cellular aggregation and productions of extracellular matrix in which colonies are embedded. There are high numbers of research in the discovery of natural and synthetic compounds which can attenuate the E. coli O157:H7 biofilm formation as well as suppress virulence-related genes. The present review article focuses on the steps involved in E. coli O157:H7 biofilm formation, factors associated with virulence and attenuation.

Ključne besede

Escherichia coli;pathogen;virulence;

Podatki

Jezik:	Angleški jezik
Leto izida:	2017
Tipologija:	1.02 - Pregledni znanstveni članek
Organizacija:	UNG - Univerza v Novi Gorici
UDK:	54
COBISS:	47096835
ISSN:	0343-8651
Št. ogledov:	1513
Št. prenosov:	0
Ocena:	0 (0 glasov)
Metapodatki:

Ostali podatki

URN:	URN:SI:UNG
Vrsta dela (COBISS):	Delo ni kategorizirano
Strani:	str. 1477-1489
Letnik:	ǂVol. ǂ74
Zvezek:	ǂno. ǂ12
Čas izdaje:	Dec. 2017
DOI:	10.1007/s00284-017-1314-y
ID:	12382286