Liposomal encapsulation of oleuropein and an olive leaf extract

molecular interactions, antioxidant effects and applications in model food systems

Rodrigo González Ortega (Avtor), Luka Šturm (Avtor), Mihaela Skrt (Avtor), Carla Di Mattia (Avtor), Paola Pittia (Avtor), Nataša Poklar Ulrih (Avtor)

Povzetek

The influence of actively/passively encapsulated oleuropein on DPPC liposomes thermal and structural properties, and its antioxidant capacity against lipid peroxidation were investigated. Also, an oleuropein-rich olive leaf extract was encapsulated in soy phosphatidylcholine (PL-90 g) and incorporated in model and commercial drinks. Oleuropein induced a concentration-dependent broadening and splitting of the gel-to-liquid phase transition temperature. Fluorescence measurements revealed a fluidizing effect on liposomes below their gel-to-liquid phase transition temperature, and a higher lipid ordering above, especially to active encapsulation. Oleuropein also showed an antioxidant effect against lipid peroxidation in PL-90 g liposomes. PL-90 g Liposomes with olive leaf extract showed a mean diameter of 405 ± 4 nm and oleuropein encapsulation efficiency of 34% and delayed oleuropein degradation at pH 2.0 and 2.8 model drinks. In conclusion, greater effects were observed on the structure and fluidity of DPPC liposomes when oleuropein was actively encapsulated, while its incorporation into acidic foods in encapsulated form could enhance its stability.

Ključne besede

liposomi;enkapsulacija;oljka;Olea europaea;rastlinski ekstrakti;listi oljke;oleuropein;fosfolipidne membrane;

Podatki

Jezik:	Angleški jezik
Leto izida:	2021
Tipologija:	1.01 - Izvirni znanstveni članek
Organizacija:	UL BF - Biotehniška fakulteta
UDK:	577.3:634.63:615.014.6
COBISS:	33992195
ISSN:	1557-1858
Št. ogledov:	191
Št. prenosov:	67
Ocena:	0 (0 glasov)
Metapodatki:

Ostali podatki

Sekundarni jezik:	Slovenski jezik
Sekundarne ključne besede:	liposomi;enkapsulacija;oljka;Olea europaea;rastlinski ekstrakti;listi oljke;oleuropein;fosfolipidne membrane;
Vrsta dela (COBISS):	Članek v reviji
Strani:	str. 84-97
Zvezek:	ǂVol. ǂ16
Čas izdaje:	2021
DOI:	10.1007/s11483-020-09650-y
ID:	14110143