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Št. zadetkov: 3
Important and specific role for basophils in acute allergic reactions
Peter Korošec, Bernhard F. Gibbs, Matija Rijavec, Adnan Custovic, Paul J. Turner
Pregledni znanstveni članek
Oznake: allergy and immunology;basophils;anaphylaxis;
IgE-mediated allergic reactions involve the activation of effector cells, predominantly through the high-affinity IgE receptor (FceRI) on mast cells and basophils. Although the mast cell is considered the major effector cell during acute allergic reactions, more recent studies indicate a potentially ...
Leto: 2018 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Mast cell activation test in the diagnosis of allergic disease and anaphylaxis
Rajia Bahri, Adnan Custovic, Peter Korošec, Marina Tsoumani, Martin Barron, Jiakai Wu, Rebekah Sayers, Alf Weimann, Monica Ruiz-Garcia, Nandinee Patel, Mira Šilar
Izvirni znanstveni članek
Oznake: basophil activation test;BAT;mast cell activation test;
Background. Food allergy is an increasing public health issue and the commonest cause of life-threatening anaphylactic reactions. Conventional allergy tests assess for the presence of allergen-specific IgE, significantly overestimating the rate of true clinical allergy resulting in over-diagnosis an ...
Leto: 2018 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Integrative transcriptomic analysis in human and mouse model of anaphylaxis identifies gene signatures associated with cell movement, migration and neuroinflammatory signalling
Matija Rijavec, Matija Rijavec, Aleš Maver, Paul J. Turner, Keli Hočevar, Mitja Košnik, Amnah Yamani, Simon P. Hogan, Adnan Custovic, Borut Peterlin, Peter Korošec
Izvirni znanstveni članek
Oznake: gibanje celic;migracija;transcriptome analysis;cell movement;migration;neuroinflammatory signaling;lipid activating nuclear receptors signaling;
Background: Anaphylaxis is an acute life-threatening allergic reaction and a concern at a global level; therefore, further progress in understanding the underlying mechanisms and more effective strategies for diagnosis, prevention and management are needed. Objective: We sought to identify the globa ...
Leto: 2022 Vir: Biotehniška fakulteta (UL BF)
Št. zadetkov: 3
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