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Št. zadetkov: 9
Angiogenin and vascular endothelial growth factor expression in lungs of lung cancer patients
Aleš Rozman, Mira Šilar, Mitja Košnik
Izvirni znanstveni članek
Oznake:
Background. Lung cancer is the leading cause of cancer deaths. Angiogenesis iscrucial process in cancer growth and progression. This prospective study evaluated expression of two central regulatory molecules: angiogenin and vascular endothelial growth factor (VEGF) in patients with lung cancer. Pati ...
Leto: 2012 Vir: Onkološki inštitut Ljubljana (OI)
Quantitative, absolute count-based T cell analysis of CD69 upregulation as a new methodology for in vitro diagnosis of delayed-type nickel hypersensitivity
Ana Koren, Mira Šilar, Helena Rupnik, Mihaela Zidarn, Peter Korošec
Izvirni znanstveni članek
Oznake: CD69;
Background: T cells play a major role in delayed-type hypersensitivity reactions. Their reactivity can be assessed by measuring the upregulation of the activation marker CD69, followed by proliferation and cytokine production. The aim of our study was to develop a novel, whole blood-based, quantitat ...
Leto: 2019 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Hymenoptera venom anaphylaxis induce a large but reversible decrease of blood basophil number
Peter Korošec, Mira Šilar, Nina Čelesnik Smodiš, Renato Eržen, Mihaela Zidarn, Mitja Košnik
Objavljeni povzetek znanstvenega prispevka na konferenci
Oznake: medicina;medicinska imunologija;alergija;imunski odziv;
Background: The pathogenic role of basophils in Hymenoptera venom anaphylaxisis not completely understood. Furthermore, there is also a lack of potential cellular biomarkers for anaphylaxis. Method: Fifteen patients were recruited from the University Clinic emergency unit as close as possible after ...
Leto: 2012 Vir: Repozitorij Univerze v Ljubljani (RUL)
Test aktivacije bazofilcev (BAT) v in vitro diagnostiki pri preobčutljivosti za strup kožekrilcev
Andreja Premoša, Mira Šilar, Renato Eržen, Nisera Bajrović, Ema Mušič, Mitja Košnik, Peter Korošec
Izvirni znanstveni članek
Oznake:
Background The basophil activation test relies on flow cytometric quantitationof the expression of the markers on the surface of basophils, after stimulation with the amount of allergen that cross-link IgE antibodies bound on their surface. In allergy diagnosis, the technique has been applied in the ...
Leto: 2008 Vir: dLib.si Digitalna knjižnica Slovenije
Transcription factors gene expression in chronic rhinosinusitis with and without nasal polyps
Tanja Soklič, Matija Rijavec, Mira Šilar, Ana Koren, Izidor Kern, Irena Hočevar-Boltežar, Peter Korošec
Izvirni znanstveni članek
Oznake: chronic rhinosinusitis;
Background. Chronic rhinosinusitis (CRS) current therapeutic approaches still fail in some patients with severe persistent symptoms and recurrences after surgery. We aimed to evaluate the master transcription factors gene expression levels of T cell subtypes in chronic rhinosinusitis with nasal poly ...
Leto: 2019 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
CD3+CD4-CD8- mucosal T cells are associated with uncontrolled chronic rhinosinusitis with nasal polyps
Tanja Soklič, Mira Šilar, Matija Rijavec, Ana Koren, Izidor Kern, Irena Hočevar-Boltežar, Peter Korošec
Kratki znanstveni prispevek
Oznake: chronic rhinosinusitis;CD3+ T-cells;CD4- T-cells;CD8- T-cells;
Increased mucosal double-negative (DN) CD3+CD4-CD8- T cells were found for the first time in CRS and were much more abundant in uncontrolled CRSwNP than in well-controlled CRSwNP.
Leto: 2019 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Systemic and airway oxidative stress in competitive swimmers
Sabina Škrgat-Kristan, Peter Korošec, Izidor Kern, Mira Šilar, Julij Gyula Šelb, Matjaž Fležar, Robert Marčun
Izvirni znanstveni članek
Oznake: bronchial hyperresponsiveness;competitive swimmers;training;
Background: The environment in swimming pools, which contain chlorine, might interact with the airway epithelium, resulting in oxidative stress and/or inflammation during high intensity training periods. Methods: We evaluated pulmonary functional (metacholine challenge test, FEV1 and VC), cellular ( ...
Leto: 2018 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
ǂThe ǂculprit insect but not severity of allergic reactions to bee and wasp venom can be determined by molecular diagnosis
Pia Gattinger, Christian Lupinek, Lampros Kalogiros, Mira Šilar, Mihaela Zidarn, Peter Korošec, Christine Koessler, Natalija Novak, Rudolf Valenta, Irene Mittermann
Izvirni znanstveni članek
Oznake: bee;wasp;venom;sting reactions;molecular diagnosis;systemic reactions;
Background. Allergy to bee and wasp venom can lead to life-threatening systemic reactions. The identification of the culprit species is important for allergen-specific immunotherapy. Objectives. To determine a panel of recombinant bee and wasp allergens which is suitable for the identification of be ...
Leto: 2018 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Mast cell activation test in the diagnosis of allergic disease and anaphylaxis
Rajia Bahri, Adnan Custovic, Peter Korošec, Marina Tsoumani, Martin Barron, Jiakai Wu, Rebekah Sayers, Alf Weimann, Monica Ruiz-Garcia, Nandinee Patel, Mira Šilar
Izvirni znanstveni članek
Oznake: basophil activation test;BAT;mast cell activation test;
Background. Food allergy is an increasing public health issue and the commonest cause of life-threatening anaphylactic reactions. Conventional allergy tests assess for the presence of allergen-specific IgE, significantly overestimating the rate of true clinical allergy resulting in over-diagnosis an ...
Leto: 2018 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Št. zadetkov: 9
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