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Št. zadetkov: 5
Art v 1 IgE epitopes of patients and humanized mice are conformational
Maja Zabel, Milena Weber, Bernhard Kratzer, Cordula Köhler, Beatrice Jahn-Schmid, Gabriele Gadermaier, Pia Gattinger, Urška Bidovec, Peter Korošec, Ursula Smole, Rudolf Valenta, Rudolf Valenta, Winfried F. Pickl, Winfried F. Pickl
Izvirni znanstveni članek
Oznake: alergija za pelod pelina;epitop IgE;specifična imunoterapija;mugwort pollen allergy;IgE epitope;allergen-specific immunotherapy;
Background. Worldwide, pollen of the weed mugwort (Artemisia vulgaris) is a major cause of severe respiratory allergy, with its major allergen, Art v 1, being the key pathogenic molecule for millions of patients. Humanized mice transgenic for a human T-cell receptor specific for the major Art v 1 T- ...
Leto: 2022 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Glycosylation enhances allergenic activity of major bee venom allergen Api m 1 by adding IgE epitopes
Pia Gattinger, Urška Bidovec, Mihaela Zidarn, Peter Korošec, Rudolf Valenta, Irene Mittermann
Kratki znanstveni prispevek
Oznake: insect venom allergy;Api m 1;allergen;glycosylation;allergenic activity;
Glycosylation enhances allergenic activity of major bee venom allergen Api m 1 by adding IgE epitopes
Leto: 2021 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Recombinant glycoproteins resembling carbohydrate-specific IgE epitopes from plants, venoms and mites
Pia Gattinger, Irene Mittermann, Christian Lupinek, Gerhard Hofer, Walter Keller, Urška Bidovec, Peter Korošec, Christine Koessler, Natalija Novak, Rudolf Valenta
Izvirni znanstveni članek
Oznake: recombinant glycoproteins;molecular allergology;component-resolved diagnosis;
Background: N-linked glycans present in venoms, pollen and mites are recognized by IgE antibodies from >20% of allergic patients but have low or no allergenic activity. Objectives: To engineer recombinant glycoproteins resembling carbohydrate-specific IgE epitopes from venoms, pollen and mites which ...
Leto: 2019 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
ǂThe ǂculprit insect but not severity of allergic reactions to bee and wasp venom can be determined by molecular diagnosis
Pia Gattinger, Christian Lupinek, Lampros Kalogiros, Mira Šilar, Mihaela Zidarn, Peter Korošec, Christine Koessler, Natalija Novak, Rudolf Valenta, Irene Mittermann
Izvirni znanstveni članek
Oznake: bee;wasp;venom;sting reactions;molecular diagnosis;systemic reactions;
Background. Allergy to bee and wasp venom can lead to life-threatening systemic reactions. The identification of the culprit species is important for allergen-specific immunotherapy. Objectives. To determine a panel of recombinant bee and wasp allergens which is suitable for the identification of be ...
Leto: 2018 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Towards personalization of asthma treatment according to trigger factors
Katarzyna Niespodziana, Kristina Borochova, Petra Pazderova, Thomas Schlederer, Natalia Astafyeva, Tatiana Baranovskaya, Mohamed-Ridha Barbouche, Evgenyi Beltiukov, Angelika Berger, Elena Borzova, Jean Bousquet, Mihaela Zidarn, Rudolf Valenta
Izvirni znanstveni članek
Oznake: wheeze;
Asthma is a severe and chronic disabling disease affecting more than 300 million people world-wide. While in the past few drugs for treatment of asthma were available, new treatment options are currently emerging which appear to be highly effective in certain subgroups of patients. Accordingly there ...
Leto: 2020 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Št. zadetkov: 5
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