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Št. zadetkov: 2
Synthetic cannabinoid WIN 55,212–2 inhibits growth and induces cell death of oral and pancreatic stem-like/poorly differentiated tumor cells
Meng-Wei Ko, Barbara Breznik, Emanuela Senjor, Anahid Jewett
Izvirni znanstveni članek
Oznake: rakave matične celice;kanabinoidi;celična smrt;biologija raka;genetska toksikologija;cancer stem cells;cannabinoids;cell death;cancer biology;genetic toxicology;
We report here that synthetic cannabinoid WIN 55,212–2 inhibits tumor cell proliferation and induces cell death of oral and pancreatic tumor cells, and the effect is much more pronounced on stem-like/poorly differentiated OSCSCs and MP2 cells when compared to well-differentiated OSCCs, and PL-12 tum ...
Leto: 2022 Vir: Nacionalni inštitut za biologijo (NIB)
Infiltrating natural killer cells bind, lyse and increase chemotherapy efficacy in glioblastoma stem-like tumorospheres
Barbara Breznik, Meng-Wei Ko, Christopher Tse, Po-Chun Chen, Emanuela Senjor, Bernarda Majc, Anamarija Habič, Nicolas Angelillis, Metka Novak, Vera Župunski, Jernej Mlakar, David Nathanson, Anahid Jewett
Izvirni znanstveni članek
Oznake: glioblastom;naravne celice ubijalke;translacijska onkologija;glioblastoma;natural killer cells;translational oncology;
Glioblastomas remain the most lethal primary brain tumors. Natural killer (NK) cell-based therapy is a promising immunotherapeutic strategy in the treatment of glioblastomas, since these cells can select and lyse therapy-resistant glioblastoma stem-like cells (GSLCs). Immunotherapy with super-charge ...
Leto: 2022 Vir: Nacionalni inštitut za biologijo (NIB)
Št. zadetkov: 2
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