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Št. zadetkov: 4
Molecular mechanisms of local anesthetic toxicity
Boris Rijavec, Boris Rijavec, Mensur Salihović, Tomislav Mirković
Pregledni znanstveni članek
Oznake: local anesthetics;local anesthetic systemic toxicity;tissue-specific toxicity;bupivacaine;lidocaine;
Local anesthetics are widely used across local and regional anesthesia, pain medicine, emergency care, and dentistry. Their therapeutic effect is based mainly on reversible voltage-gated sodium channel inhibition, but toxicity is not limited to this mechanism. This narrative review integrates molecu ...
Leto: 2026 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Molecular mechanisms of acute drug toxicity in polypharmacy
Nikolina Rijavec, Boris Rijavec
Pregledni znanstveni članek
Oznake: analgetiki;psihotropna zdravila;akutna toksičnost;citokorm p450;analgesics;psychotropic drugs;polypharmacy;acute toxicity;cytochrome P450;
Concurrent exposure to analgesic and psychotropic drugs is frequent in patients with pain, psychiatric comorbidity, frailty, or acute-care needs. The clinically important question is whether analgesics and psychotropic drugs act on the same metabolic, transporter, receptor, ion-channel, or cellular ...
Leto: 2026 Vir: Univerzitetna psihiatrična klinika Ljubljana (UPK)
Effectiveness of ultrasound-guided canal adductor blockade for chronic pain and functioning in knee osteoarthritis
Mensur Salihović, Mensur Salihović, Boris Rijavec, Anida Muratagić, Rok Blagus, Urška Puh
Izvirni znanstveni članek
Oznake: osteoartritis;koleno;blokada kanala z ultrazvočnim vodenjem;zdravila;osteoarthritis;knee;ultrasound-guided canal blockade;
Background and Objective. Knee osteoarthritis is a serious epidemiological problem that causes severe pain and impairs abilities. We investigated the effects of adductor canal blockade (ACB) on chronic osteoarthritis knee pain, motor function, and mobility. Methods. Seventy-seven patients with chron ...
Leto: 2022 Vir: Medicinska fakulteta (UL MF)
Sur l’étude scientifique des avant-gardes. Problèmes et thèmes
Tomaž Brejc, Darko Dolinar, Milček Komelj, Evald Koren, Alenka Koron, Janko Kos, Lado Kralj, Peter Krečič, Borut Loparnik, Neda Pagon Brglez, Boris Paternu, Andrej Rijavec, Majda Stanovnik, Jola Škulj, Igor Zabel
Ni določena
Oznake: l’art de l’avant-garde slovène comme objet d’étude interdisciplinaire (vues sociologiques, historiques, artistiques, littéraires, comparées)
Dans le protocole d’une discussion interdisciplinaire, l’on explique la problématique du terme d’avant-garde dans ses significations et ses emplois différents, spécialement en rapport avec le terme de modernisme. On décrit des spécialités dans le traitement des avant-gardes par des sciences particul ...
Leto: 2015 Vir: ZRC SAZU
Št. zadetkov: 4
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