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Structure-function studies of sponge-derived compounds on the cardiac CaV3.1 channel
Anne-Sophie Depuydt, Piyush A. Patel, Žan Toplak, Chinmaya Bhat, Manuela Voráčová, Irene Eteläinen, Fiammetta Vitulano, Nives Hribernik, Tihomir Tomašić, Lucija Peterlin-Mašič
Izvirni znanstveni članek
Oznake: T-type calcium channels;ion channels;purpurealidin I;bromotyrosines;marine-derived bioactive compounds;
T-type calcium (CaV3) channels are involved in cardiac automaticity, development, and excitation–contraction coupling in normal cardiac myocytes. Their functional role becomes more pronounced in the process of pathological cardiac hypertrophy and heart failure. Currently, no CaV3 channel inhibitors ...
Leto: 2023 Vir: Fakulteta za farmacijo (UL FFA)
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