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Membrane palmitoylated protein 7 is required for osteogenesis and is linked with bone mineralisation and osteoporosis: the functional evaluation of GEFOS GWAS hit
Petra Malavašič, Jasna Lojk, Nika Lovšin, Radko Komadina, Gregor Haring, Rihard Trebše, Fernando Rivadeneira, David Karasik, Barbara Ostanek, Janja Marc
Izvirni znanstveni članek
Oznake: MPP7;adipogenesis;HOS cell lineage;human bone tissue;human muscle tissue;
Genome-wide association studies have identified multiple loci associated with bone mineral density, a major determinant of osteoporotic fracture risk. At one such locus, genetic, bioinformatic, and zebrafish knockout data strongly prioritize membrane palmitoylated protein 7 (MPP7) as a candidate gen ...
Leto: 2025 Vir: Fakulteta za farmacijo (UL FFA)
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