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DEPTOR cell-autonomously promotes adipogenesis, and its expression is associated with obesity
Mathieu Laplante, Simon Horvat, William T. Festuccia, Kivanc Birsoy, Zala Prevoršek, Alejo Efeyan, David M. Sabatini
Izvirni znanstveni članek
Oznake: molekularna genetika;debelost;DEPTOR;
DEP domain-containig mTOR-interacting protein (DEPTOR) inhibits the mechanistic target of rapamty-cin (mTOR), but its in vivo functions are unknown. Previous work indicates that Deptor is part of the Fob3a quantitative trait locus (QTL) linked to obesity/leanness in mice, with Deptor expression bein ...
Leto: 2012 Vir: Biotehniška fakulteta (UL BF)
Personalized Medicine
Rebecca Henderson , Darlene Solomon , Jose B. Cibelli , Benjamin Cravatt , David Sabatini
Video in druga učna gradiva
Oznake: medicine;personalized medicine
We've deciphered the human genome and moved into proteomics-the study of the individual proteins that the genes code for. Such advances anticipate the day when drugs are not only targeted at molecular workings or specific diseases but tailor-made for each individual's genetic makeup.
Leto: 2002 Vir: videolectures.net
Št. zadetkov: 2
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