Št. zadetkov: 17
Izvirni znanstveni članek
Oznake:
microRNA;screening;vasculitis;
Anti-neutrophil cytoplasm antibody (ANCA)-associated vasculitis (AAV) comprises autoimmune disease entities that cause target organ damage due to relapsing-remitting small vessel necrotizing vasculitis, and which affects various vascular beds. The pathogenesis of AAV is incompletely understood, whic ...
Leto:
2022
Vir:
Medicinska fakulteta (UL MF)
Izvirni znanstveni članek
Oznake:
colorectal adenoma;colorectal carcinoma;metastases;intra-tumour heterogeneity;epithelial-mesenchymal transition;miR-200 family;target genes;
MicroRNAs of the miR-200 family have been shown experimentally to regulate epithelialmesenchymal transition (EMT). Although EMT is the postulated mechanism of development and progression of colorectal cancer (CRC), there are still limited and controversial data on expression of miR-200 family and th ...
Leto:
2019
Vir:
Medicinska fakulteta (UL MF)
Izvirni znanstveni članek
Oznake:
extracellular matrix;colorectal carcinoma;colorectal polyps;
Colorectal carcinoma usually evolves gradually, forming a spectrum of lesions, due to accumulation of genetic mutations and epigenetic alterations. Many early lesions are detected since the introduction of screening programs. The greatest challenge is to distinguish between adenomas with epithelial ...
Leto:
2020
Vir:
Medicinska fakulteta (UL MF)
Izvirni znanstveni članek
Oznake:
colorectal cancer;differentially expressed genes;cancer stem cells;
Significant progress has been made in the last decade in our understanding of the pathogenetic mechanisms of colorectal cancer (CRC). Cancer stem cells (CSC) have gained much attention and are now believed to play a crucial role in the pathogenesis of various cancers, including CRC. In the current s ...
Leto:
2021
Vir:
Medicinska fakulteta (UL MF)
Izvirni znanstveni članek
Oznake:
web aplication;RNA expression;colorectal cancer;gene expression;knowledge base;cancer genome atlas;miRNA;mRNA;gene correlation;target genes;
"miRNA colorectal cancer" (https://mirna-coadread.omics.si/) is a freely available web application for studying microRNA and mRNA expression and their correlation in colorectal cancer. To the best of our knowledge, %miRNA colorectal cancer% has the largest knowledge base of miRNA-target gene express ...
Leto:
2019
Vir:
Medicinska fakulteta (UL MF)
Pregledni znanstveni članek
Oznake:
mikroRNA (miRNA);presaditev ledvic;imunski odziv;microRNA (miRNA);kidney transplantation;immune response;
MicroRNAs (miRNAs) are members of the non-coding regulatory RNA family that play pivotal roles in physiological and pathological conditions, including immune response. They are particularly interesting as promising therapeutic targets, prognostic and diagnostic markers due to their easy detection in ...
Leto:
2021
Vir:
Medicinska fakulteta (UL MF)
Izvirni znanstveni članek
Oznake:
kolorektalni karcinom;metastaze v jetrih;metastaze v bezgavkah;colorectal carcinoma;liver metastasis;lymph node metastasis;
Decorin (DCN) is one of the matricellular proteins that participate in normal cells’ function as well as in cancerogenesis. While its expression in primary tumours is well known, there is limited data about its expression in metastases. Furthermore, the post-transcriptional regulation of DCN is stil ...
Leto:
2022
Vir:
Medicinska fakulteta (UL MF)
Izvirni znanstveni članek
Oznake:
glioblastoma;radiotherapy;chemotherapy;
Background. Glioblastoma (GBM) is the most common and the most malignant glioma subtype. Among numerous genetic alterations, miRNAs contribute to pathogenesis of GBM and it is suggested that also to GBM recurrence and resistance to therapy. Based on publications, we have selected 11 miRNAs and analy ...
Leto:
2018
Vir:
Repozitorij Univerze v Ljubljani (RUL)
Izvirni znanstveni članek
Oznake:
Crohn's disease;fibrosis;stenosis;pathology;pathogenesis;
Background: Despite significant progress in the research of fibrosis in various organs, fibrosis remains a poorly understood complication of Crohn's disease (CD). We analyzed pathologic features of fibrosis and inflammation in CD and compared them with the normal bowel, aiming to clarify whether fib ...
Leto:
2020
Vir:
Medicinska fakulteta (UL MF)
Doktorska disertacija
Oznake:
patologija;mikrobiologija;
Rak debelega črevesa in danke (RDČD) je posledica kopičenja morfoloških in (epi)genetskih sprememb. Kljub poznavanju histopatoloških značilnosti je pri mnogih lezijah postavitev pravilne diagnoze zaradi netipične histopatološke slike zahtevna. V pomoč bi lahko bili označevalci, specifični za različn ...
Leto:
2021
Vir:
Medicinska fakulteta (UL MF)