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Št. zadetkov: 5
Epithelial-mesenchymal transition-related micrornas and their target genes in colorectal cancerogenesis
Branislava Ranković, Nina Zidar, Margareta Žlajpah, Emanuela Boštjančič
Izvirni znanstveni članek
Oznake: colorectal adenoma;colorectal carcinoma;metastases;intra-tumour heterogeneity;epithelial-mesenchymal transition;miR-200 family;target genes;
MicroRNAs of the miR-200 family have been shown experimentally to regulate epithelialmesenchymal transition (EMT). Although EMT is the postulated mechanism of development and progression of colorectal cancer (CRC), there are still limited and controversial data on expression of miR-200 family and th ...
Leto: 2019 Vir: Medicinska fakulteta (UL MF)
Expression of extracellular matrix-related genes and their regulatory microRNAs in problematic colorectal polyps
Margareta Žlajpah, Emanuela Boštjančič, Bojan Tepeš, Nina Zidar
Izvirni znanstveni članek
Oznake: extracellular matrix;colorectal carcinoma;colorectal polyps;
Colorectal carcinoma usually evolves gradually, forming a spectrum of lesions, due to accumulation of genetic mutations and epigenetic alterations. Many early lesions are detected since the introduction of screening programs. The greatest challenge is to distinguish between adenomas with epithelial ...
Leto: 2020 Vir: Medicinska fakulteta (UL MF)
Identification and validation of new cancer stem cell-related genes and their regulatory microRNAs in colorectal cancerogenesis
Kristian Urh, Margareta Žlajpah, Nina Zidar, Emanuela Boštjančič
Izvirni znanstveni članek
Oznake: colorectal cancer;differentially expressed genes;cancer stem cells;
Significant progress has been made in the last decade in our understanding of the pathogenetic mechanisms of colorectal cancer (CRC). Cancer stem cells (CSC) have gained much attention and are now believed to play a crucial role in the pathogenesis of various cancers, including CRC. In the current s ...
Leto: 2021 Vir: Medicinska fakulteta (UL MF)
Differential expression of decorin in metastasising colorectal carcinoma is regulated by miR-200c and long non-coding RNAs
Margareta Žlajpah, Kristian Urh, Jan Grosek, Nina Zidar, Emanuela Boštjančič
Izvirni znanstveni članek
Oznake: kolorektalni karcinom;metastaze v jetrih;metastaze v bezgavkah;colorectal carcinoma;liver metastasis;lymph node metastasis;
Decorin (DCN) is one of the matricellular proteins that participate in normal cells’ function as well as in cancerogenesis. While its expression in primary tumours is well known, there is limited data about its expression in metastases. Furthermore, the post-transcriptional regulation of DCN is stil ...
Leto: 2022 Vir: Medicinska fakulteta (UL MF)
Geni zunajceličnega matriksa kot označevalci invazije v neoplazmah debelega črevesa in danke
Margareta Žlajpah, Nina Zidar, Emanuela Boštjančič, Danijel Petrovič, Petra Hudler, Primož Strojan
Doktorska disertacija
Oznake: patologija;mikrobiologija;
Rak debelega črevesa in danke (RDČD) je posledica kopičenja morfoloških in (epi)genetskih sprememb. Kljub poznavanju histopatoloških značilnosti je pri mnogih lezijah postavitev pravilne diagnoze zaradi netipične histopatološke slike zahtevna. V pomoč bi lahko bili označevalci, specifični za različn ...
Leto: 2021 Vir: Medicinska fakulteta (UL MF)
Št. zadetkov: 5
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