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Št. zadetkov: 8
Skeletal muscle microvascular dysfunction in obesity-related insulin resistance
Chiedozie Kenneth Ugwoke, Erika Cvetko, Nejc Umek, Nejc Umek
Pregledni znanstveni članek
Oznake: microvascular dysfunction;insulin resistance;obesity treatment;
Obesity is a worrisomely escalating public health problem globally and one of the leading causes of morbidity and mortality from noncommunicable disease. The epidemiological link between obesity and a broad spectrum of cardiometabolic disorders has been well documented; however, the underlying patho ...
Leto: 2022 Vir: Medicinska fakulteta (UL MF)
ǂThe ǂeffect of glucose metabolism disorder on capillary network and myosin heavy chain expression in skeletal muscles of mice
Nejc Umek, Erika Cvetko, Ida Eržen, Danijel Petrovič, Tomaž Marš, Barbara Radochová
Doktorska disertacija
Oznake: debelost;zmanjšana občutljivost na inzulin;skeletna mišica;kapilarizacija;tip mišičnih vlaken;kopičenje znotrajceličnih lipidov;
Uvod: Presnovne motnje, povezane z debelostjo, so eden glavnih vzrokov obolevnosti in umrljivosti v razvitem svetu. Strukturne in funkcionalne spremembe v skeletnih mišicah in kapilarni mreži so pomembno povezane z mehanizmi zmanjšane občutljivosti na inzulin zaradi debelosti. V poznih fazah debelos ...
Leto: 2021 Vir: Medicinska fakulteta (UL MF)
Application of FTIR spectroscopy to detect changes in skeletal muscle composition due to obesity with insulin resistance and STZ-induced diabetes
Barbara Zupančič, Nejc Umek, Chiedozie Kenneth Ugwoke, Erika Cvetko, Simon Horvat, Jože Grdadolnik
Izvirni znanstveni članek
Oznake: medicina;diabetes;debelost;mišji modeli;skeletne mišice;makromolekularna sestava;spektroskopija;FTIR;
Application of FTIR spectroscopy to detect changes in skeletal muscle composition due to obesity with insulin resistance and STZ-induced diabetes
Leto: 2022 Vir: Kemijski inštitut (KI)
Nevrotoksičnost in vnetni odgovor pri diabetičnih miših po vnosu bupivakaina v liposomih
Liljana Markova, Erika Cvetko, Tatjana Stopar Pintarič, Dušan Šuput, Mirt Kamenik, Metoda Lipnik-Štangelj
Doktorska disertacija
Oznake: anesteziologija;patofiziologija;Sladkorna bolezen;Disertacije;Spremljajoči zapleti;Vnetja;Periferna nevropatija;Diabetično spremenjeni živci;Kirurgija;Lokalna anestezija;Toksikologija;Lokalni anestetiki;Stranski učinki;Bupivakain;
Uvod Pojavnost sladkorne bolezni v svetu narašča. Bolniki s sladkorno boleznijo potrebujejo dvakrat več kirurških posegov kot bolniki brez sladkorne bolezni. Zaradi spremljajočih bolezni ima področna anestezija pogosto prednost pred splošno anestezijo, ni pa povsem raziskano, koliko je pri sladkorni ...
Leto: 2021 Vir: Medicinska fakulteta (UL MF)
ǂThe ǂinfluence of diabetic peripheral neuropathy on the duration of sciatic nerve block with 1.3% liposomal bupivacaine and 0.25% bupivacaine hydrochloride in a mouse model
Liljana Markova, Erika Cvetko, Chiedozie Kenneth Ugwoke, Simon Horvat, Nejc Umek, Tatjana Stopar Pintarič
Izvirni znanstveni članek
Oznake: medicina;sladkorna bolezen;periferna nevropatija;farmakologija;anestetiki;laboratorijske miši;
Little is known regarding the pharmacological properties of extended-release local anesthetics in the setting of diabetic peripheral neuropathy. We investigated and compared the duration of sciatic nerve block following administration of clinically relevant concentrations of liposomal bupivacaine (L ...
Leto: 2022 Vir: Medicinska fakulteta (UL MF)
Clinical and histologic tissue responses of skin incisions closed with glycomer 631 and lactomer 9-1 using a subcuticular technique in pigs
Tanja Plavec, Tanja Švara, Irena Zdovc, Mitja Gombač, Marija Damjanovska, Tatjana Stopar Pintarič, Erika Cvetko, Alenka Seliškar
Izvirni znanstveni članek
Oznake: dermatologic surgical procedures - veterinary;skin - anatomy and histology;suture techniques;wound healing;swine;absorbable suture material;glycomer 631;lactomer 9–1;tissue reaction;Trueperella pyogenes;pig;
Background: Glycomer 631 and lactomer 9–1 are absorbable suture materials indicated for soft tissue approximation in non-infected wounds. Pigs are often used as surgical models in translational research; however, reports of tissue reactions to both suture materials in pigs are limited. The aim of th ...
Leto: 2020 Vir: Veterinarska fakulteta (UL VF)
Neurotoxicity of bupivacaine and liposome bupivacaine after sciatic nerve block in healthy and streptozotocin-induced diabetic mice
Liljana Markova, Nejc Umek, Simon Horvat, Admir Hadžić, Maxine M. Kuroda, Tatjana Stopar Pintarič, Vesna Mrak, Erika Cvetko
Izvirni znanstveni članek
Oznake: bupivakain hidroklorid;diabetes;nevrotoksičnost;injicirana suspenzija liposomskega bupivakina;periferalna nevropatija;bupivacaine hydrochloride;neurotoxicity;liposome bupivacaine injectable suspension;peripheral neuropathy;
Background: Long-acting local anaesthetics (e.g. bupivacaine hydrochloride) or sustained-release formulations of bupivacaine (e.g. liposomal bupivacaine) may be neurotoxic when applied in the setting of diabetic neuropathy. The aim of the study was to assess neurotoxicity of bupivacaine and liposome ...
Leto: 2020 Vir: Medicinska fakulteta (UL MF)
Exploration of macromolecular phenotype of human skeletal muscle in diabetes using infrared spectroscopy
Barbara Zupančič, Barbara Zupančič, Chiedozie Kenneth Ugwoke, Mohamed Elwy Abdelmonaem, Armin Alibegović, Erika Cvetko, Jože Grdadolnik, Anja Šerbec, Nejc Umek, Nejc Umek
Izvirni znanstveni članek
Oznake: diabetes mellitus;skeletal muscle;metabolism;macromulecular composition;infrared spectroscopy;multivariate analysis;histochemical assays;
Introduction: The global burden of diabetes mellitus is escalating, and more efficient investigative strategies are needed for a deeper understanding of underlying pathophysiological mechanisms. The crucial role of skeletal muscle in carbohydrate and lipid metabolism makes it one of the most suscept ...
Leto: 2023 Vir: Kemijski inštitut (KI)
Št. zadetkov: 8
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