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Št. zadetkov: 5
Suicide and changes in expression of neuronal mirna predicted by an algorithm search through miRNA databases
Alja Videtič, Urban Alič, Tomaž Zupanc, Katarina Kouter, Katarina Kouter
Izvirni znanstveni članek
Oznake: psihiatrija;epigenetika;samomorilno vedenje;psychiatry;epigenetics;suicidal behaviour;
Suicide is multifactorial and polygenic phenotype, affected by environmental and genetic factors. Among epigenetic mechanisms, miRNAs have been studied, but so far no very concise results exist. To overcome limitations of candidate miRNA and whole genome sequencing approaches, we created an in silic ...
Leto: 2022 Vir: Medicinska fakulteta (UL MF)
Metilacija DNA pri slovenskih moških, žrtvah samomora z obešanjem
Katarina Kouter, Alja Videtič, Tomaž Zupanc
Doktorska disertacija
Oznake: samomori;samomorilno vedenje;Slovenija;molekularna genetika;epigenetika;samomorilci;možgani;genom;sekvenciranje naslednje generacije;genetika, biokemična;psihiatrija;
Samomorilno vedenje je poligensko, večfaktorsko vedenje, ki prizadane ljudi širom sveta. Na samomorilno vedenje vplivajo številni biološki in zunanji dejavniki, ki jih lahko povežemo z epigenetiko. Mehanizmi in dejavniki samomorilnega vedenja kljub širokemu naboru novih dognanj niso v celoti poznani ...
Leto: 2019 Vir: Medicinska fakulteta (UL MF)
Targeted sequencing approach
Katarina Kouter, Tomaž Zupanc, Alja Videtič, Alja Videtič
Izvirni znanstveni članek
Oznake: suicidal behaviour;epigenetics;next-generation sequencing;
Objectives Epigenetic mechanisms are involved in regulation of many pathologies, including suicidal behaviour. However, the factors through which epigenetics affect suicidal behaviour are not fully understood. Methods We analysed DNA methylation of eight neuropsychiatric genes (NR3C1, SLC6A4, HTR1A, ...
Leto: 2022 Vir: Medicinska fakulteta (UL MF)
Dynamic intercell communication between glioblastoma and microenvironment through extracellular vesicles
Gloria Krapež, Katarina Kouter, Ivana Jovchevska, Ivana Jovchevska, Alja Videtič
Pregledni znanstveni članek
Oznake: eksosom;mikrookolje;vnetje;exosome;microenvironment;inflammation;
Glioblastoma is simultaneously the most common and most aggressive primary brain tumor in the central nervous system, with poor patient survival and scarce treatment options. Most primary glioblastomas reoccur and evolve radio- and chemoresistant properties which make them resistant to further treat ...
Leto: 2022 Vir: Medicinska fakulteta (UL MF)
Epigenetics of Alzheimer's disease
Matea Nikolac Perkovic, Alja Videtič, Marcela Konjevod, Katarina Kouter, Dubravka Svob Strac, Gordana Nedic Erjavec, Nela Pivac
Pregledni znanstveni članek
Oznake: Alzheimerjeva bolezen;epigenetika;metilacija DNA;Alzheimer's disease;epigenetics;DNA methylation;
There are currently no validated biomarkers which can be used to accurately diagnose Alzheimer's disease (AD) or to distinguish it from other dementia-causing neuropathologies. Moreover, to date, only symptomatic treatments exist for this progressive neurodegenerative disorder. In the search for new ...
Leto: 2021 Vir: Medicinska fakulteta (UL MF)
Št. zadetkov: 5
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