Št. zadetkov: 18
Izvirni znanstveni članek
Oznake:
suicidal behaviour;epigenetics;next-generation sequencing;
Objectives Epigenetic mechanisms are involved in regulation of many pathologies, including suicidal behaviour. However, the factors through which epigenetics affect suicidal behaviour are not fully understood. Methods We analysed DNA methylation of eight neuropsychiatric genes (NR3C1, SLC6A4, HTR1A, ...
Leto:
2022
Vir:
Medicinska fakulteta (UL MF)
Pregledni znanstveni članek
Oznake:
nanomateriali;rak možganov;nanomedicina;nanomaterials;brain cancer;nanomedicine;
Advances in technology of the past decades led to development of new nanometer scale diagnosis and treatment approaches in cancer medicine leading to establishment of nanooncology. Inorganic and organic nanomaterials have been shown to improve bioimaging techniques and targeted drug delivery systems ...
Leto:
2019
Vir:
Medicinska fakulteta (UL MF)
Pregledni znanstveni članek
Oznake:
Suicide is a complex phenomenora that is triggered by environmental factors, and probably partially also by genetic code. Genetic studies performed on suicide brain contributed interesting, findings on serotonergic, dopaminergic and noradrenergic neurotransmitter systems and on cholesterol system as ...
Leto:
2006
Vir:
dLib.si Digitalna knjižnica Slovenije
Video in druga učna gradiva
Oznake:
medicine;psychiatry
Leto:
2012
Vir:
videolectures.net
Doktorska disertacija
Oznake:
duševne motnje;samomori;patogeneza;nevrotrofini;receptorji;možganski nevrotrofni dejavnik;genotipizacija;epigenetika;metilacija DNA;gensko izražanje;možgani;kri;Slovenia;Slovenija;
Povezava genetskih in epigenetskih sprememb v genih nevrotrofnega sistema s samomorom
Leto:
2017
Vir:
Medicinska fakulteta (UL MF)
Pregledni znanstveni članek
Oznake:
dolgo nekodirana RNA;shizofrenija;depresija;long noncoding RNA;schizophrenia;depression;
Understanding the pathology of psychiatric disorders is challenging due to their complexity and multifactorial origin. However, development of high-throughput technologies has allowed for better insight into their molec-ular signatures. Advancement of sequencing methodologies have made it possible t ...
Leto:
2021
Vir:
Medicinska fakulteta (UL MF)
Pregledni znanstveni članek
Oznake:
glioblastom;možganski rak;nekodirani genom;biološki označevalec;prognoza;glioblastoma;brain cancer;noncoding genome;biomarker;prognosis;
Glioblastoma is the most aggressive and lethal primary brain malignancy, with an average patient survival from diagnosis of 14 months. Glioblastoma also usually progresses as a more invasive phenotype after initial treatment. A major step forward in our understanding of the nature of glioblastoma wa ...
Leto:
2020
Vir:
Medicinska fakulteta (UL MF)
Pregledni znanstveni članek
Oznake:
glioblastoma;extracellular vesicles;nanoscience;
Owing to the advancement of technology combined with our deeper knowledge of human nature and diseases, we are able to move towards precision medicine, where patients are treated at the individual level in concordance with their genetic profiles. Lately, the integration of nanoparticles in biotechno ...
Leto:
2020
Vir:
Medicinska fakulteta (UL MF)
Doktorska disertacija
Oznake:
samomori;samomorilno vedenje;Slovenija;molekularna genetika;epigenetika;samomorilci;možgani;genom;sekvenciranje naslednje generacije;genetika, biokemična;psihiatrija;
Samomorilno vedenje je poligensko, večfaktorsko vedenje, ki prizadane ljudi širom sveta. Na samomorilno vedenje vplivajo številni biološki in zunanji dejavniki, ki jih lahko povežemo z epigenetiko. Mehanizmi in dejavniki samomorilnega vedenja kljub širokemu naboru novih dognanj niso v celoti poznani ...
Leto:
2019
Vir:
Medicinska fakulteta (UL MF)
Magistrsko delo
Oznake:
depression;DNA methylation;BDNF;COMT;SLC6A4;cell-free DNA;
Depression is a common and heterogeneous mental disorder. When a patient, diagnosed with depression, does not achieve an adequate response to treatment with at least two antidepressants, it is considered that patient has developed a treatment-resistant depression (TRD). As an alternative treatment f ...
Leto:
2020
Vir:
Fakulteta za kemijo in kemijsko tehnologijo (UL FKKT)