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Št. zadetkov: 2
Asymmetric T-segment binding and gate dynamics govern the final stages of the type IIA topoisomerase catalytic cycle
Kristina Stevanović, Barbara Herlah, Matic Pavlin, Andrej Perdih
Izvirni znanstveni članek
Oznake: biokemija;topoizomeraza IIα;DNK;molekulska dinamika;type IIA DNA topoisomerase;T-segment;C-gate;catalytic cycle;molecular dynamics;
Type IIA DNA topoisomerases are molecular nanomachines that alter DNA topology during essential cellular processes. The final steps of their catalytic cycle, after translocation of the transported (T-) segment into the C- gate, are still not fully understood. Here, we performed all-atom molecular dy ...
Leto: 2025 Vir: Kemijski inštitut (KI)
Polynuclear silver(I)–quinoxaline complex
Ghada Bouz, Nevena Lj. Stevanović, Marta Kasunič, Tina P. Andrejević, Iztok Turel, Ondřej Jand’ourek, Klára Konečná, Žiko Milanović, Kristina Milisavljević, Biljana Đ. Glišić
Izvirni znanstveni članek
Oznake: N-substituirani kinoksalin-2-karboksamidi;srebrovi(I) kompleksi;antimikrobna aktivnost;interakcije z DNA;interakcija s proteini;N-substituted quinoxaline-2-carboxamides;silver(I) complexes;antimycobacterial activity;DNA interaction;protein interaction;
Background: Silver(I) complexes with aromatic heterocyclic ligands are well known for their broad antimicrobial potential, largely attributed to their ability to interact with biomolecular targets. Results and Discussion: In this study, a new polynuclear silver(I) complex with N-(3′-phenylpropyl)qui ...
Leto: 2026 Vir: Fakulteta za kemijo in kemijsko tehnologijo (UL FKKT)
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