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Št. zadetkov: 4
High-sensitivity C-reactive protein and carotid intima media thickness as markers of subclinical inflammation and atherosclerosis in pediatric patients with hypercholesterolemia
Lana Blinc, Matej Mlinarič, Tadej Battelino, Urh Grošelj
Pregledni znanstveni članek
Oznake: familial hypercholesterolemia;polygenic hypercholesterolemia;inflammation;atherosclerosis;carotid intima media thickness;cIMT;C-reactive protein;hsCRP;
Hypercholesterolemia is a major cause of atherosclerosis development and premature cardiovascular disease (CVD). It leads to inflammation, which further accelerates atherosclerosis progression. Familial hypercholesterolemia (FH) is an autosomal dominant disorder characterized by elevated serum LDL-c ...
Leto: 2020 Vir: Medicinska fakulteta (UL MF)
Standardised and systematic sampling of public engagement in brain health
Ida Muc, Lana Blinc, Gaj Vidmar, Slavko Kurdija, Tina Vovk, Mara Bresjanac
Izvirni znanstveni članek
Oznake: ozaveščenost;preventiva;anketa;nevrološke motnje;prevention;awareness;survey;neurological disorders;representative sampling;
Neurological and mental health disorders are a major global challenge. A block of brain health-related questions was embedded into the standardised Slovenian Public Opinion survey (online and on paper) to gain an updated insight into public interest and engagement in brain health. Representative sam ...
Leto: 2025 Vir: Fakulteta za družbene vede (UL FDV)
Novel NIR DDNP-type solvatochromic and fluorogenic probes for amyloid β detection
Matic Rogan, Lana Blinc, Luka Rejc, Bruno Aleksander Martek, Uroš Vezonik, Ines Babnik, Damijan Knez, Jerneja Kladnik, Janez Košmrlj, Blagoj Mukaetov, Ana Brodnik, Anže Meden, Matej Jaklin, Mara Bresjanac, Stanislav Gobec
Raziskovalni podatki
Oznake: amyloid β;DDNP;fluorescent sensor;molecular rotor;NIR;optical properties;solvatochromism;
This dataset contains experimental data related to the characterization of fluorophores, their in vitro and ex vivo evaluation for detection of amyloid beta aggregates as well as molecular docking studies.
Leto: 2026 Vir: Fakulteta za kemijo in kemijsko tehnologijo (UL FKKT)
Probing Alzheimer's pathology
Luka Rejc, Damijan Knez, Gabriela Molina-Aguirre, Alba Espargaró, Jerneja Kladnik, Anže Meden, Lana Blinc, Matic Lozinšek, Ross D. Jansen-van Vuuren, Matic Rogan, Bruno Aleksander Martek, Jernej Mlakar, Ana Dremelj, Andrej Petrič, Stanislav Gobec, Mara Bresjanac, Janez Košmrlj
Izvirni znanstveni članek
Oznake: amyloid beta;fluorophore;solvatochromism;synthesis;photophysics;
Fluorescent probes are a powerful tool for imaging amyloid β (Aβ) plaques, the hallmark of Alzheimer’s disease (AD). Herein, we report the synthesis and comprehensive characterization of 21 novel probes as well as their optical properties and binding affinities to Aβ fibrils. One of these dyes, 1Ae, ...
Leto: 2024 Vir: Fakulteta za kemijo in kemijsko tehnologijo (UL FKKT)
Št. zadetkov: 4
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