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Št. zadetkov: 12
Odvisnost endocitotske aktivnosti urotelijskih celic od njihove diferenciacijske stopnje in mikrotubulov
Larisa Tratnjek, Mateja Erdani-Kreft
Diplomsko delo
Oznake: sečni mehur;urotelij;uroplakini;mikrotubuli;diferenciacija;endocitoza;
Odvisnost endocitotske aktivnosti urotelijskih celic od njihove diferenciacijske stopnje in mikrotubulov
Leto: 2009 Vir: Biotehniška fakulteta (UL BF)
Vitamin A and retinoids in bladder cancer chemoprevention and treatment
Larisa Tratnjek, Jera Jeruc, Rok Romih, Daša Zupančič
Pregledni znanstveni članek
Oznake: bladder cancer;vitamin A;retinoic acid signalling;
Bladder cancer (BC) is the tenth most common cancer worldwide with a high recurrence rate, morbidity and mortality. Therefore, chemoprevention and improved treatment of BC are of paramount importance. Epidemiological studies suggest that adequate vitamin A intake may be associated with reduced BC ri ...
Leto: 2021 Vir: Medicinska fakulteta (UL MF)
Neuroinflammation-induced upregulation of glial cathepsin X expression and activity in vivo
Anja Pišlar, Larisa Tratnjek, Gordana Glavan, Nace Zidar, Marko Živin, Janko Kos
Izvirni znanstveni članek
Oznake: živčno vnetje;katepsin X;neuroinflammation;neurodegeneration;lipopolysaccharide;glia;cathepsin X;neuroprotection;
Neuroinflammation is an important factor in pathogenesis of neurodegenerative diseases. Microglia-derived lysosomal cathepsins have been increasingly recognized as important inflammatory mediators that trigger signalling pathways that aggravate neuroinflammation. In vitro, a contribution to neuroinf ...
Leto: 2020 Vir: Fakulteta za farmacijo (UL FFA)
Integrated light and electron microscopy workflow for morphological, molecular and ultrastructural analysis of spheroids
Larisa Tratnjek, Aleksandar Janev, Nataša Resnik, Uroš Cerkvenik, Mateja Erdani-Kreft
Raziskovalni podatki
Oznake: bladder cancer;light microscopy and electron microscopy;protocols;sample preparation;spheroids;urothelial cells;
The dataset presented here supports an integrated light and electron microscopy workflow for comprehensive morphological, molecular, and ultrastructural characterization of three-dimensional (3D) spheroid models. The data accompany a submitted data paper and are discussed in a submitted original res ...
Leto: 2025 Vir: Medicinska fakulteta (UL MF)
Standardization of esophageal adenocarcinoma in vitro model and its applicability for model drug testing
Larisa Tratnjek, Nadica Sibinovska, Slavko Kralj, Darko Makovec, Katja Kristan, Mateja Erdani-Kreft
Izvirni znanstveni članek
Oznake: esophageal adenocarcinoma;FLO-1 cell line;disease pathophysiology;
FLO-1 cell line represents an important tool in esophageal adenocarcinoma (EAC) research as a verified and authentic cell line to study the disease pathophysiology and antitumor drug screenings. Since in vitro characteristics of cells depend on the microenvironment and culturing conditions, we perfo ...
Leto: 2021 Vir: Medicinska fakulteta (UL MF)
ǂThe ǂantibacterial activity of human amniotic membrane against multidrug-resistant bacteria associated with urinary tract infections
Taja Železnik, Larisa Tratnjek, Aleksandar Janev, Katja Seme, Marjanca Starčič Erjavec, Mateja Erdani-Kreft
Izvirni znanstveni članek
Oznake: amniotic membrane homogenate;MRSA;antibiotic resistance;
Urinary tract infections (UTIs) represent a serious global health issue, especially due to emerging multidrug-resistant UTI-causing bacteria. Recently, we showed that the human amniotic membrane (hAM) could be a candidate for treatments and prevention of UPEC and Staphylococcus aureus infections. Ho ...
Leto: 2021 Vir: Medicinska fakulteta (UL MF)
In vitro ciliotoxicity and cytotoxicity testing of repeated chronic exposure to topical nasal formulations for safety studies
Larisa Tratnjek, Nadica Sibinovska, Katja Kristan, Katja Kristan, Mateja Erdani-Kreft, Mateja Erdani-Kreft
Izvirni znanstveni članek
Oznake: formulacije zdravil za nos;mukociliarni očistek;citotoksičnost;nasal drug formulations;mucociliary clearance;cytotoxicity;
Certain active drugs and excipients of nasal formulations may impair ciliary function and mucociliary clearance. The ciliary beat frequency (CBF) is a key parameter for determining mucociliary clearance rate, and in vitro assessments of CBF have proven to be accurate and reproducible. Since topical ...
Leto: 2021 Vir: Medicinska fakulteta (UL MF)
Detrimental effect of various preparations of the human amniotic membrane homogenate on the 2D and 3D bladder cancer in vitro models
Aleksandar Janev, Taja Železnik, Larisa Tratnjek, Žiga Sardoč, Hristina Obradović, Slavko Mojsilović, Milena Taskovska, Tomaž Smrkolj, Mateja Erdani-Kreft
Izvirni znanstveni članek
Oznake: rak sečnega mehurja;urotelij;2D in 3D in vitro modeli;elektronski mikroskop;proliferacija;urologija;
Despite being among the ten most common cancers with high recurrence rates worldwide, there have been no major breakthroughs in the standard treatment options for bladder cancer in recent years. The use of a human amniotic membrane (hAM) to treat cancer is one of the promising ideas that have emerge ...
Leto: 2021 Vir: Medicinska fakulteta (UL MF)
Cytotoxic activity of LLO Y406A is targeted to the plasma membrane of cancer urothelial cells
Nataša Resnik, Larisa Tratnjek, Mateja Erdani-Kreft, Matic Kisovec, Saša Rezelj, Apolonija Bedina Zavec, Gregor Anderluh, Marjetka Podobnik, Peter Veranič
Izvirni znanstveni članek
Oznake: biokemija;rakave celice;listeriolizin O;toksini;
Identification of novel agents for bladder cancer treatment is highly desirable due to the high incidence of tumor recurrence and the risk of progression to muscle-invasive disease. The key feature of the cholesterol-dependent toxin listeriolysin O mutant (LLO Y406A) is its preferential activity at ...
Leto: 2021 Vir: Medicinska fakulteta (UL MF)
ǂThe ǂefficient magneto-mechanical actuation of cancer cells using a very low concentration of non-interacting ferrimagnetic hexaferrite nanoplatelets
Tanja Goršak, Eva Jarc Jovičić, Larisa Tratnjek, Igor Križaj, Borja Sepulveda, Josep Nogues, Mateja Erdani-Kreft, Toni Petan, Slavko Kralj, Darko Makovec
Izvirni znanstveni članek
Oznake: cancer cells;
Magneto-mechanical actuation (MMA) using the low-frequency alternating magnetic fields (AMFs) of magnetic nanoparticles internalized into cancer cells can be used to irreparably damage these cells. However, nanoparticles in cells usually agglomerate, thus greatly augmenting the delivered force compa ...
Leto: 2024 Vir: Institut Jožef Stefan (IJS)
Št. zadetkov: 12
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