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Št. zadetkov: 5
Pipette tip with integrated electrodes for gene electrotransfer of cells in suspension
Matej Reberšek, Maša Kandušer, Damijan Miklavčič
Izvirni znanstveni članek
Oznake: elektrode;genska elektrotransfekcija;koničasta komora;CHO celična linija;electrodes;gene electrotransfer;pipette tip;CHO cell line;
Pipette tip with integrated electrodes for gene electrotransfer of cells in suspension
Leto: 2011 Vir: Repozitorij Univerze v Ljubljani (RUL)
Načrtovanje strategij za vzpostavitev dobre laboratorijske prakse za delo z gensko spremenjenimi organizmi II. varnostnega razreda v pogojih in vitro
Fendi Friedl, Nataša Karas Kuželički, Maša Kandušer
Magistrsko delo
Oznake: gensko spremenjeni organizem;varnostni razred;zaprti sistem;kontaminacija;zadrževalni ukrepi;
Gensko spremenjeni organizem (GSO) je organizem, z izjemo človeka, ali mikroorganizem, katerega genski material je spremenjen s postopki, ki spreminjajo genski material drugače, kot to poteka v naravnih razmerah. Lahko je potencialno nevaren, toksičen, ali ima možnost nenadzorovanega širjenja. GSO r ...
Leto: 2021 Vir: Fakulteta za farmacijo (UL FFA)
Cell size dynamics and viability of cells exposed to hypotonic treatment and electroporation for electrofusion optimization
Marko Ušaj, Katja Trontelj, Rosana Hudej, Maša Kandušer, Damijan Miklavčič
Izvirni znanstveni članek
Oznake: hypotonic treatment;cell swelling;regulatory volume decrease;cell size measurements;viability;electrofusion;electroporation;
Background. Various electrofusion parameters have to be adjusted to obtain theoptimal electrofusion efficiency. Based on published data, good electrofusion conditions can be achieved with the hypotonic treatment. However, the duration of the hypotonic treatment before electroporation and buffer hypo ...
Leto: 2009 Vir: Repozitorij Univerze v Ljubljani (RUL)
Inhibition of p38 MAPK or immunoproteasome overcomes resistance of chronic lymphocytic leukemia cells to Bcl-2 antagonist venetoclax
Damjan Avsec, Marja Škrlj, Tilen Burnik, Maša Kandušer, Maruša Rajh, Helena Podgornik, Irena Mlinarič-Raščan
Izvirni znanstveni članek
Oznake:
Chronic lymphocytic leukemia (CLL) is a hematological neoplasm of CD19-positive mature-appearing B lymphocytes. Despite the clinical success of targeted therapies in CLL, the development of resistance diminishes their therapeutic activity. This is also true for the Bcl-2 antagonist venetoclax. We in ...
Leto: 2022 Vir: Fakulteta za farmacijo (UL FFA)
Targeting autophagy triggers apoptosis and complements the action of venetoclax in chronic lymphocytic leukemia cells
Damjan Avsec, Alma Tana Jakoš Djordjevič, Maša Kandušer, Helena Podgornik, Matevž Škerget, Irena Mlinarič-Raščan
Izvirni znanstveni članek
Oznake: avtofagi;odpornost na zdravila;tarčna terapija;chronic lymphocytic leukemia;autophagy;AMPK/ULK1;venetoclax;drug resistance;targeted therapy;
Continuous treatment of patients with chronic lymphocytic leukemia (CLL) with venetoclax, an antagonist of the anti-apoptotic protein Bcl-2, can result in resistance, which highlights the need for novel targets to trigger cell death in CLL. Venetoclax also induces autophagy by perturbing the Bcl-2/B ...
Leto: 2021 Vir: Fakulteta za farmacijo (UL FFA)
Št. zadetkov: 5
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