Iskalni niz:
išči po
išči po
išči po
išči po
Vrsta gradiva:
Jezik:
Št. zadetkov: 4
Vpliv metformina na rakave celice v kulturi v odvisnosti od razpoložljivih hranil
Maruša Rajh, Mojca Pavlin, Sergej Pirkmajer
Doktorska disertacija
Oznake: metabolizem rakavih celic;metformin;2-deoksi-D-glukoza;AMPK;rakave celice;rak dojke;koncentracija hranil;luščenje živih celic;disertacije;
Metformin se uporablja za zdravljenje sladkorne bolezni in nedavne raziskave so nakazale, da ima morda protirakave učinke. Cilj doktorske disertacije je bil proučiti delovanje metformina na rakave celice v odvisnosti od razpoložljivih hranil v gojišču. Pri tem smo primerjali učinke metformina na kla ...
Leto: 2018 Vir: Fakulteta za elektrotehniko (UL FE)
Inhibition of p38 MAPK or immunoproteasome overcomes resistance of chronic lymphocytic leukemia cells to Bcl-2 antagonist venetoclax
Damjan Avsec, Marja Škrlj, Tilen Burnik, Maša Kandušer, Maruša Rajh, Helena Podgornik, Irena Mlinarič-Raščan
Izvirni znanstveni članek
Oznake:
Chronic lymphocytic leukemia (CLL) is a hematological neoplasm of CD19-positive mature-appearing B lymphocytes. Despite the clinical success of targeted therapies in CLL, the development of resistance diminishes their therapeutic activity. This is also true for the Bcl-2 antagonist venetoclax. We in ...
Leto: 2022 Vir: Fakulteta za farmacijo (UL FFA)
Suppression of pyruvate dehydrogenase kinase by dichloroacetate in cancer and skeletal muscle cells is isoform specific and partially independent of HIF-1[alpha]
Nives Škorja, Klemen Dolinar, Katarina Miš, Urška Matkovič, Maruša Rajh, Mojca Pavlin, Matej Podbregar, Sergej Pirkmajer, Sergej Pirkmajer
Izvirni znanstveni članek
Oznake: celice skeletnih mišic;rak;dikloroacetat;skeletal muscle cells;cancer;dichloroacetate;
Inhibition of pyruvate dehydrogenase kinase (PDK) emerged as a potential strategy for treatment of cancer and metabolic disorders. Dichloroacetate (DCA), a prototypical PDK inhibitor, reduces the abundance of some PDK isoenzymes. However, the underlying mechanisms are not fully characterized and may ...
Leto: 2021 Vir: Medicinska fakulteta (UL MF)
Proposing urothelial and muscle in vitro cell models as a novel approach for assessment of long-term toxicity of nanoparticles
Matej Skočaj, Maruša Rajh, Klemen Strojan, Jasna Lojk, Mateja Erdani-Kreft, Katarina Miš, Sergej Pirkmajer, Vladimir Boštjan Bregar, Peter Veranič, Mojca Pavlin
Izvirni znanstveni članek
Oznake: nanotoksikologija;in vitro L6 mišična celična linija;urotelij;diferenciacija;celična signalizacija;ROS;nanotoxicology;in vitro L6 rat skeletal muscle cell line;urothelium in vitro;differentiation;cell signaling;
Many studies evaluated the short-term in vitro toxicity of nanoparticles (NPs); however, long-term effects are still not adequately understood. Here, we investigated the potential toxic effects of biomedical (polyacrylic acid and polyethylenimine coated magnetic NPs) and two industrial (SiO$_2$ and ...
Leto: 2020 Vir: Fakulteta za elektrotehniko (UL FE)
Št. zadetkov: 4
Ključne besede:
Leto izdaje:
Avtorji:
Repozitorij:
Tipologija:
Jezik: