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Št. zadetkov: 2
Phenylalanine-tRNA aminoacylation is compromised by ALS/FTD-associated C9orf72 C4G2 repeat RNA
Mirjana Malnar, Urša Čerček, Xiaoke Yin, Manh Tin Ho, Barbka Repič-Lampret, Manuela Neumann, Andreas Hermann, Guy Rouleau, Beat Suter, Manuel Mayr, Boris Rogelj
Izvirni znanstveni članek
Oznake: genetic mutation;aminoacylation;amyotrophic lateral sclerosis;frontotemporal dementia;
The expanded hexanucleotide GGGGCC repeat mutation in the C9orf72 gene is the main genetic cause of amyotrophic lateral sclerosis and frontotemporal dementia. Under one disease mechanism, sense and antisense transcripts of the repeat are predicted to bind various RNA-binding proteins, compromise the ...
Leto: 2023 Vir: Institut Jožef Stefan (IJS)
First-year dynamics of the anaerobic microbiome and archaeome in infants’ oral and gastrointestinal systems
Charlotte Neumann, Rokhsareh Mohammadzadeh, Pei Yee Woh, Tanja Kobal, Manuela-Raluca Pausan, Polona Mertelj
Izvirni znanstveni članek
Oznake: črevesni mikrobiom;prebavni trakt (GIT);ustni mikrobiom;razvoj dojenčkov;zgodnje življenje;metagenomika;anaerobi;arheje;breastfeeding;infants;gut microbiome;GIT;oral microbiome;infant development;early life;metagenomics;anaerobes;archaea;strain tracking;source tracking;
Recent research provides new insights into the early establishment of the infant gut microbiome, emphasizing the influence of breastfeeding on the development of gastrointestinal microbiomes. In our study, we longitudinally examined the taxonomic and functional dynamics of the oral and gastrointesti ...
Leto: 2024 Vir: Nacionalni inštitut za biologijo (NIB)
Št. zadetkov: 2
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