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Št. zadetkov: 5
Identification and description of molecular transport mechanisms across cell membrane due to electroporation
Maria Scuderi, Lea Rems, Janja Dermol-Černe
Doktorska disertacija
Oznake: electroporation;electrochemotherapy;cisplatin;numerical modeling;molecu-lar transport;
Electroporation is a phenomenon which results in transient increase in cell membrane permeability for ions and molecules when exposing biological cells to short high-voltage electric pulses. If cells survive the exposure to electric pulses, electroporation is called reversible; otherwise, if cells d ...
Leto: 2024 Vir: Fakulteta za elektrotehniko (UL FE)
ǂThe ǂuse of high-frequency short bipolar pulses in cisplatin electrochemotherapy in vitro
Maria Scuderi, Matej Reberšek, Damijan Miklavčič, Janja Dermol-Černe
Izvirni znanstveni članek
Oznake: electroporation;electrochemotherapy;high-frequency bipolar pulses;cisplatin;cell survival;drug uptake;
ǂThe ǂuse of high-frequency short bipolar pulses in cisplatin electrochemotherapy in vitro
Leto: 2019 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Analysis of magnetic resonance contrast agent entrapment following reversible electroporation in vitro
Marko Stručić, Damijan Miklavčič, Zala Vidic, Maria Scuderi, Igor Serša, Matej Kranjc
Izvirni znanstveni članek
Oznake: electroporation;membrane permeabilization;magnetic resonance contrast agent;T1 relaxometry;
Background. Administering gadolinium-based contrast agent before electroporation allows the contrast agent to enter the cells and enables MRI assessment of reversibly electroporated regions. The aim of this study was evaluation of contrast agent entrapment in CHO cells and comparison of these result ...
Leto: 2024 Vir: Fakulteta za elektrotehniko (UL FE)
ǂThe ǂequivalence of different types of electric pulses for electrochemotherapy with cisplatin − an in vitro study
Maria Scuderi, Janja Dermol-Černe, Janez Ščančar, Stefan Marković, Lea Rems, Damijan Miklavčič
Izvirni znanstveni članek
Oznake: electrochemotherapy;electroporation;cisplatin uptake;phenomenological model;equivalent puls parameters;
Background Electrochemotherapy (ECT) is a treatment involving the administration of chemotherapeutics drugs followed by the application of 8 square monopolar pulses of 100 μs duration at a repetition frequency of 1 Hz or 5000 Hz. However, there is increasing interest in using alternative types of pu ...
Leto: 2024 Vir: Fakulteta za elektrotehniko (UL FE)
Models of electroporation and the associated transmembrane molecular transport should be revisited
Maria Scuderi, Janja Dermol-Černe, Clarissa Amaral da Silva, Aswin Muralidharan, Pouyan E. Boukany, Lea Rems
Izvirni znanstveni članek
Oznake: elektropermeabilizacija;matematično modeliranje;elektrodifuzija;transport molekul;multifizika;modeliranje na več ravneh;electropermeabilization;mathematical modeling;electrodiffusion;molecular transport;multiphysics;multiscale;
Electroporation has become a powerful tool for nonviral delivery of various biomolecules such as nucleic acids, proteins, and chemotherapeutic drugs to virtually any living cell by exposing the cell membrane to an intense pulsed electric field. Different multiphysics and multiscale models have been ...
Leto: 2022 Vir: Fakulteta za elektrotehniko (UL FE)
Št. zadetkov: 5
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