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Št. zadetkov: 3
Prediction of California Bearing Ratio (CBR) and ompaction characteristics of granular soils
Attique ul Rehman, Khalid Farooq, Hassan Mujtaba
Izvirni znanstveni članek
Oznake: CBR;regression;model;prediction;compaction characteristics;
This research is an effort to correlate the index properties of granular soils with the California Bearing Ratio (CBR) and the compaction characteristics. Soil classification, modified proctor and CBR tests conforming to the relevant ASTM methods were performed on natural as well as composite sand s ...
Leto: 2017 Vir: Fakulteta za gradbeništvo, prometno inženirstvo in arhitekturo (UM FGPA)
Structure-guided design of D-galactal derivatives with high affinity and selectivity for the galectin-8 n-terminal domain
Mujtaba Hassan, Floriane Baussière, Samo Guzelj, Anders Sundin, Maria Håkansson, Rebeka Kovačič, Hakon Leffler, Tihomir Tomašić, Marko Anderluh, Žiga Jakopin
Izvirni znanstveni članek
Oznake: Galectin-8N;d-galactal;benzimidazole;selectivity;X-ray crystallography;cytokine secretion;
Galectin-8 is a carbohydrate-binding protein that plays a crucial role in tumor progression and metastasis, antibacterial autophagy, modulation of the immune system, and bone remodeling. The design, synthesis, and protein affinity evaluation of a set of C-3 substituted benzimidazole and quinoline d- ...
Leto: 2021 Vir: Fakulteta za farmacijo (UL FFA)
Benzimidazole-galactosides bind selectively to the galectin-8 N-terminal domain
Mujtaba Hassan, Sjors van Klaveren, Maria Håkansson, Carl Diehl, Rebeka Kovačič, Floriane Baussière, Anders Sundin, Jaka Dernovšek, Marko Anderluh, Tihomir Tomašić, Žiga Jakopin
Izvirni znanstveni članek
Oznake: benzimidazole;galectin-8N;quinoline;selectivity;molecular dynamics;x-ray crystallography;
We have obtained the X-ray crystal structure of the galectin-8 N-terminal domain (galectin-8N) with a previously reported quinoline-galactoside ligand at a resolution of 1.6Å. Based on this X-ray structure, a collection of galactosides derivatised at O3 with triazole, benzimidazole, benzothiazole, a ...
Leto: 2021 Vir: Fakulteta za farmacijo (UL FFA)
Št. zadetkov: 3
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