Št. zadetkov: 22
Pregledni znanstveni članek
Oznake:
mikroRNA (miRNA);presaditev ledvic;imunski odziv;microRNA (miRNA);kidney transplantation;immune response;
MicroRNAs (miRNAs) are members of the non-coding regulatory RNA family that play pivotal roles in physiological and pathological conditions, including immune response. They are particularly interesting as promising therapeutic targets, prognostic and diagnostic markers due to their easy detection in ...
Leto:
2021
Vir:
Medicinska fakulteta (UL MF)
Izvirni znanstveni članek
Oznake:
SARS-CoV-2;immunolabelling;microscopy;
Background: There is increasing evidence that identification of SARS-CoV-2 virions by transmission electron microscopy could be misleading due to the similar morphology of virions and ubiquitous cell structures. This study thus aimed to establish methods for indisputable proof of the presence of SAR ...
Leto:
2021
Vir:
Medicinska fakulteta (UL MF)
Izvirni znanstveni članek
Oznake:
microRNA;screening;vasculitis;
Anti-neutrophil cytoplasm antibody (ANCA)-associated vasculitis (AAV) comprises autoimmune disease entities that cause target organ damage due to relapsing-remitting small vessel necrotizing vasculitis, and which affects various vascular beds. The pathogenesis of AAV is incompletely understood, whic ...
Leto:
2022
Vir:
Medicinska fakulteta (UL MF)
Izvirni znanstveni članek
Oznake:
ANCA;biomarker;glomerulonephritis;microRNA;vasculitis;epigenetics;
Introduction: Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is characterized by necrotizing small vessel vasculitis that frequently manifests as glomerulonephritis (AAV-GN). An accurate noninvasive biomarker reflecting active AAV-GN remains elusive. The knowledge of microRN ...
Leto:
2025
Vir:
Repozitorij Univerze v Ljubljani (RUL)
Kratki znanstveni prispevek
Oznake:
perineural invasion;reparative perineural hyperplasia;immunohistochemistry;
Reparative perineural hyperplasia is an incidental and probably under reported reactive histologic finding thus far only reported in the setting of healing wounds or adjacent to a dermatofibroma in cutaneous specimens. It is characterized by a focal concentric proliferation of cytologically bland sp ...
Leto:
2021
Vir:
Medicinska fakulteta (UL MF)
Doktorska disertacija
Oznake:
ANCA;vaskulitis;glomerulonefritis;mikroRNA;označevalec;epigenetika;
V doktorski disertaciji smo raziskovali patogenetski, diagnostični in napovedni pomen regulatornih kratkih nekodirajočih molekul mikro RNA (miRNA) pri vaskulitisu, povezanim s prisotnostjo protinevtrofilnih protiteles (angl. ANCA-associated vasculitis, AAV).
V multifaktorski patogenezi tkivne okvar ...
Leto:
2025
Vir:
Medicinska fakulteta (UL MF)
Pregledni znanstveni članek
Oznake:
extracellular vesicles;human biofluids;nanotechnology;atomic force microscopy;electron microscopy;morphology;
Extracellular vesicles (EVs) are nanometric membranous structures secreted from almost every cell and present in biofluids. Because EV composition reflects the state of its parental tissue, EVs possess an enormous diagnostic/prognostic potential to reveal pathophysiological conditions. However, a pr ...
Leto:
2021
Vir:
Medicinska fakulteta (UL MF)
Izvirni znanstveni članek
Oznake:
vnetne črevesne bolezni;fibroza;Crohnova bolezen;inflammatory bowel diseases;fibrosis;Crohn’s disease;
Fibrosis is an important feature of inflammatory bowel diseases (IBD), but its pathogenesis is incompletely understood. Our aim was to identify genes important for fibrosis in IBD by comparison with kidney and liver fibrosis. First, we performed bioinformatics analysis of Gene Expression Omnibus dat ...
Leto:
2022
Vir:
Medicinska fakulteta (UL MF)
Pregledni znanstveni članek
Oznake:
ANCA;glomerulonefritis;drobnožilni vaskulitis;MPO;PR3;granulomatoza s poliangiitisom;mikroskopski poliangiitis;sistemsko vnetje;
Leto:
2025
Vir:
Digitalni repozitorij raziskovalnih organizacij Slovenije
Kratki znanstveni prispevek
Oznake:
collagenofibrotic glomerulopathy;type III collagen;deposition;fibrils;electron microscopy;non-immune glomerulopathy;
We highlight an ultrastructural image of collagenofibrotic glomerulopathy, a rare disorder marked by mesangial and subendothelial type III collagen deposition, and place it within the current consensus on diagnostic criteria and clinical implications. The fibrils show a woven, thread-like pattern of ...
Leto:
2026
Vir:
Digitalni repozitorij raziskovalnih organizacij Slovenije