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Metabolomic Profiling of Extracellular Vesicles Reveals Distinct Metabolic Dysregulation and Treatment-Specific Signatures in Depression
Nikola Balic, Gordana Nedic Erjavec, Marcela Konjevod, Jorge Saiz, Tina Curkovic, Lucija Tudor, Dubravka Svob Strac, Alja Videtič, Julija Šmon, Magda Tušek-Žnidarič
Izvirni znanstveni članek
Oznake: MDD;TRD;metabolomics;extracellular vesicles;duloxetine;bright-light therapy;esketamine;treatment;
Major depressive disorder (MDD) is associated with complex metabolic alterations. In this study, we applied a multiplatform metabolomics approach (GC-MS and LC-MS) to characterize the plasma extracellular vesicle (EV) metabolome in healthy controls (N = 50), responsive MDD patients (N = 60), and pat ...
Leto: 2026 Vir: Medicinska fakulteta (UL MF)
Št. zadetkov: 1
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