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Rab3a is critical for trapping alpha-MSH granules in the high Ca2+-affinity pool by preventing constitutive exocytosis
Simon Sedej, Maša Skelin, Oliver Schlüter, Marjan Rupnik
Izvirni znanstveni članek
Oznake: melanotrophs;exocytosis;
Rab3a is a small GTPase of the Rab3 subfamily that acts during late stages of Ca2+-regulated exocytosis. Previous functional analysis in pituitary melanotrophs described Rab3a as a positive regulator of Ca2+-dependent exocytosis. However, the precise role of the Rab3a isoform on the kinetics and int ...
Leto: 2013 Vir: Medicinska fakulteta (UM MF)
Št. zadetkov: 1
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