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Št. zadetkov: 3
STAT5 as a key protein of erythropoietin signalization
Zuzana Tóthová, Jana Tomc, Nataša Debeljak, Peter Solár
Pregledni znanstveni članek
Oznake: STAT5;erythropoietin receptor;molecular mechanisms;
Erythropoietin (EPO) acts on multiple tissues through its receptor EPOR, a member of a cytokine class I receptor superfamily with pleiotropic effects. The interaction of EPO and EPOR triggers the activation of several signaling pathways that induce erythropoiesis, including JAK2/STAT5, PI3K/AKT, and ...
Leto: 2021 Vir: Medicinska fakulteta (UL MF)
Erythropoietin and its angiogenic activity
Patrícia Kimáková, Peter Solár, Zuzana Solárová, Radovan Komel, Nataša Debeljak
Pregledni znanstveni članek
Oznake: eritropoetin;receptor eritropoetina;rak;erythropoietin;erythropoietin receptor;cancer;
Erythropoietin (EPO) is the main hematopoietic hormone acting on progenitor red blood cells via stimulation of cell growth, differentiation, and anti-apoptosis. However, its receptor (EPOR) is also expressed in various non-hematopoietic tissues, including endothelium. EPO is a pleiotropic growth fac ...
Leto: 2017 Vir: Medicinska fakulteta (UL MF)
ǂThe ǂrole of PI3K/AKT and MAPK signaling pathways inerythropoietin signalization
Zuzana Tóthová, Martina Šemeláková, Zuzana Solárová, Jana Tomc, Nataša Debeljak, Peter Solár
Pregledni znanstveni članek
Oznake: eritropoetin;PI3K;MAPK;erythropoietin;
Erythropoietin (EPO) is a glycoprotein cytokine known for its pleiotropic effects on varioustypes of cells and tissues. EPO and its receptor EPOR trigger signaling cascades JAK2/STAT5,MAPK, and PI3K/AKT that are interconnected and irreplaceable for cell survival. In this article, wedescribe the role ...
Leto: 2021 Vir: Medicinska fakulteta (UL MF)
Št. zadetkov: 3
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