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Št. zadetkov: 6
Spontaneous cyclization of 2-methylthiosemicarbazones yields new 1,2,4-triazolidine-3-thiones, useful as building blocks for drug design
Simona Gričar, Marta Kasunič, Gregor Marolt, Sanja Skaro-Bogojevic, Marko Novinec, Jakob Kljun
Izvirni znanstveni članek
Oznake: 2-metiltiosemikarbazid;1,2,4-triazolidin-3-tioni;ciklizacija;zelena kemija;NDM-1;2-methylthiosemicarbazide;1,2,4-triazolidine-3-thiones;cyclization;green chemistry;
From the point of view of medicinal chemistry, thiosemicarbazones are interesting molecules as they exhibit various biological activities, such as antitumor, antifungal, antibacterial, antiviral, and antileukemic properties, and their synthesis is deeply investigated. However, the synthesis using 2- ...
Leto: 2025 Vir: Fakulteta za kemijo in kemijsko tehnologijo (UL FKKT)
Copper(II) and zinc(II) complexes with the clinically used fluconazole
Nevena Lj. Stevanović, Ivana Aleksić, Jakob Kljun, Sanja Skaro-Bogojevic, Aleksandar Veselinovic, Jasmina Nikodinović-Runić, Iztok Turel, Miloš I. Djuran, Biljana Đ. Glišić
Izvirni znanstveni članek
Oznake: baker;cink;kovinski kompleksi;
Copper(II) and zinc(II) complexes with clinically used antifungal drug fluconazole (fcz), {[CuCl$_2$(fcz)$_2$]·5H$_2$O}$_n$, 1, and {[ZnCl$_2$(fcz)$_2$]·2C$_2$H$_5$OH}$_n$, 2, were prepared and characterized by spectroscopic and crystallographic methods. The polymeric structure of the complexes comp ...
Leto: 2021 Vir: Fakulteta za kemijo in kemijsko tehnologijo (UL FKKT)
Silver(I) complexes with voriconazole as promising anti-Candida agents
Mia Stanković, Sanja Skaro-Bogojevic, Jakob Kljun, Žiko Milanović, Nevena Lj. Stevanović, Jelena Lazić, Sandra Vojnović, Iztok Turel, Miloš I. Djuran, Biljana Đ. Glišić
Izvirni znanstveni članek
Oznake: srebrovi(I) kompleksi;vorikonazol;koordinacijski polimeri;kalkulacije DFT;proti Candidna aktivnost;CYP51B;silver(I) complexes;Voriconazole;coordination polymers;DFT calculations;anti-Candida activity;
Recognizing that metal ions play an important role in modifying the pharmacological properties of known organic-based drugs, the present manuscript addresses the complexation of the antifungal agent voriconazole (vcz) with the biologically relevant silver(I) ion as a strategy for the development of ...
Leto: 2024 Vir: Fakulteta za kemijo in kemijsko tehnologijo (UL FKKT)
Clinically used antifungal azoles as ligands for gold(III) complexes
Nevena Lj. Stevanović, Jakob Kljun, Ivana Aleksić, Sanja Skaro-Bogojevic, Dušan Milivojević, Aleksandar Veselinovic, Iztok Turel, Miloš I. Djuran, Jasmina Nikodinović-Runić, Biljana Đ. Glišić
Izvirni znanstveni članek
Oznake: organokovinski kompleksi;zlato;azoli;protimikrobno delovanje;
In a search for novel antimicrobial metal-based therapeutic agents, mononuclear gold(III) complexes 1–7 of the general formula [AuCl$_3$(azole)], where azole stands for imidazole (im, 1), 1-isopropylimidazole (ipim, 2), 1-phenylimidazole (phim, 3), clotrimazole (ctz, 4), econazole (ecz, 5), tioconaz ...
Leto: 2022 Vir: Fakulteta za kemijo in kemijsko tehnologijo (UL FKKT)
Polynuclear silver(I) complex with thianthrene
Darko P. Ašanin, Tina P. Andrejević, Sanja Skaro-Bogojevic, Nevena Lj. Stevanović, Ivana Aleksić, Dušan Milivojević, Franc Perdih, Iztok Turel, Miloš I. Djuran, Biljana Đ. Glišić
Objavljeni znanstveni prispevek na konferenci
Oznake: srebro;srebrovi kompleksi;protimikrobno delovanje;interakcije z biomolekulami;
New silver(I) complex with thianthrene (tia), [Ag(NO$_3$)(tia)(H$_2$O)]$_n$, was synthesized by the reaction of AgNO$_3$ with an equimolar amount of tia in ethanol/dichloromethane (v/v 1:1) at room temperature, and characterized by NMR, IR and UV-Vis spectroscopy and single-crystal X-ray diffraction ...
Leto: 2020 Vir: Fakulteta za kemijo in kemijsko tehnologijo (UL FKKT)
Structural characterization, antimicrobial activity and BSA/DNA binding affinity of new silver(I) complexes with thianthrene and 1,8-naphthyridine
Darko P. Ašanin, Sanja Skaro-Bogojevic, Franc Perdih, Tina P. Andrejević, Dušan Milivojević, Ivana Aleksić, Jasmina Nikodinović-Runić, Biljana Đ. Glišić, Iztok Turel, Miloš I. Djuran
Izvirni znanstveni članek
Oznake: srebro(I);srebrovi kompleksi;
Three new silver(I) complexes [Ag(NO$_3$)(tia)(H$_2$O)]$_n$ (Ag1), [Ag(CF$_3$SO$_3$)(1,8-naph)]$_n$ (Ag2) and [Ag$_2$(1,8-naph)$_2$(H$_2$O)$_{1.2}$](PF$_6$)$_2$ (Ag3), where tia is thianthrene and 1,8-naph is 1,8-naphthyridine, were synthesized and structurally characterized by different spectroscop ...
Leto: 2021 Vir: Fakulteta za kemijo in kemijsko tehnologijo (UL FKKT)
Št. zadetkov: 6
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