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Ruthenium complexes show potent inhibition of AKR1C1, AKR1C2, and AKR1C3 enzymes and anti-proliferative action against chemoresistant ovarian cancer cell line
Jakob Kljun, Renata Pavlič, Eva Hafner, Tanja Lipec, Sara Moreno-Da Silva, Primož Tič, Iztok Turel, Iztok Turel, Tomaž Büdefeld, Jure Stojan, Tea Lanišnik-Rižner, Tea Lanišnik-Rižner
Izvirni znanstveni članek
Oznake: ruthenium complexes;synthesis;crystal structure;
In this study, we present the synthesis, kinetic studies of inhibitory activity toward aldo-keto reductase 1C (AKR1C) enzymes, and anticancer potential toward chemoresistant ovarian cancer of 10 organoruthenium compounds bearing diketonate (1–6) and hydroxyquinolinate (7–10) chelating ligands with t ...
Leto: 2022 Vir: Medicinska fakulteta (UL MF)
Crystal structure of human PCNA in complex with three p15 peptides
Matteo De March, Nekane Merino, Amaia Gonzalez-Magaña, Miguel Romano-Moreno, S. Onesti, Francisco J. Blanco-Silva, Alfredo De Biasio
Raziskovalni podatki
Oznake: crystal structure;Homo sapiens;Escherichia coli;
Crystal structure of human PCNA in complex with three p15 peptides
Leto: 2018 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Št. zadetkov: 2
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