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Characterization of genomic imprinting defects during mouse iPSC generation
Tajda Klobučar, Jernej Ogorevc, Jernej Ogorevc, Simão José Teixeira da Rocha, Simão José Teixeira da Rocha, Mojca Narat, Uroš Petrovič, Uroš Petrovič
Magistrsko delo
Oznake: induced pluripotent stem cells;genomic imprinting;DNA methylation;
Induced pluripotent stem cells (iPSCs) can be obtained from somatic cells through a dynamic process of reprogramming and represent an important step towards personalized regenerative medicine. Unfortunately, through available reprogramming protocols, iPSCs still acquire several genetic and epigeneti ...
Leto: 2020 Vir: Biotehniška fakulteta (UL BF)
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