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Št. zadetkov: 2
Metabolism of estrogens
Stefan Poschner, Judith Wackerlig, Dan Cacsire Castillo-Tong, Andrea Wolf, Isabel von der Decken, Tea Lanišnik-Rižner, Renata Pavlič, Anastasia Meshcheryakova
Izvirni znanstveni članek
Oznake: serozni rak jajčnika visoke stopnje;steroidni hormoni;metabolomics;high-grade serous ovarian cancer;steroid hormones;
High-grade serous ovarian cancer (HGSOC) is currently treated with cytoreductive surgery and platinum-based chemotherapy. The majority of patients show a primary response; however, many rapidly develop drug resistance. Antiestrogens have been studied as low toxic treatment options for HGSOC, with hi ...
Leto: 2020 Vir: Medicinska fakulteta (UL MF)
Altered profile of E1-S transporters in endometrial cancer
Renata Pavlič, Suzana Vidic, Maja Anko, Tamara Knific, Tomaž Büdefeld, Kristina Marton, Maša Sinreih, Stefan Poschner, Walter Jäger, Snježana Frković-Grazio, Tea Lanišnik-Rižner
Izvirni znanstveni članek
Oznake: rak endometrija;intrakrinologija;organski polipeptidi, ki prenašajo anione;endometrial cancer;intracrinology;organic anion-transporting polypeptides;
Endometrial cancer (EC) is associated with increased estrogen actions. Locally, estrogens can be formed from estrone-sulphate (E1-S) after cellular uptake by organic anion-transporting polypeptides (OATP) or organic anion transporters (OAT). Efflux of E1-S is enabled by ATP Binding Cassette transpor ...
Leto: 2021 Vir: Medicinska fakulteta (UL MF)
Št. zadetkov: 2
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