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Št. zadetkov: 4
Klinični pomen genetskih sprememb v genu za kalretikulin (CALR) pri bolnikih z mieloproliferativnimi novotvorbami
Tanja Belčič Mikič, Matjaž Sever, Samo Zver
Doktorska disertacija
Oznake: hematologija;
Uvod: V septembru 2013 je bila pri večini bolnikov, ki nimajo mutacije v genu JAK2 V61F in MPL (JAK2 V617F- in MPL-negativni bolniki) z esencialno trombocitemijo (ET) ugotovljena somatska mutacija v genu za kalretikulin (CALR). Prepoznana je bila tudi pri nekaterih bolnikih z drugimi podvrstami miel ...
Leto: 2020 Vir: Medicinska fakulteta (UL MF)
ǂThe ǂcontemporary approach to CALR-positive myeloproliferative neoplasms
Tanja Belčič Mikič, Tadej Pajič, Samo Zver, Matjaž Sever
Pregledni znanstveni članek
Oznake: kalcij;mieloproliferativne neoplazme;diagnostika;trombocitemija;umetna inteeligenca;calreticulin;chaperone;calcium;myeloproliferative neoplasm;diagnostics;thrombocythemia;artificial intelligence;
CALR mutations are a revolutionary discovery and represent an important hallmark of myeloproliferative neoplasms (MPN), especially essential thrombocythemia and primary myelofibrosis. To date, several CALR mutations were identified, with only frameshift mutations linked to the diseased phenotype. It ...
Leto: 2021 Vir: Medicinska fakulteta (UL MF)
Management of anticoagulant-related nephropathy
Tanja Belčič Mikič, Nika Kojc, Maja Frelih, Andreja Aleš, Željka Večerić-Haler
Izvirni znanstveni članek
Oznake: anticoagulant related nephropathy;ARN;warfarin nephropathy;anticoagulant kidney disease;glomerular hemorrhage;anticoagulants;DOACs;NOACs;
Background: Anticoagulant-related nephropathy (ARN) is a form of acute kidney injury that mainly occurs in patients with previously unrecognized glomerular disease in addition to excessive anticoagulation. Since a renal biopsy is not performed in most cases, the diagnosis is often presumptive. Metho ...
Leto: 2021 Vir: Medicinska fakulteta (UL MF)
Is it possible to predict clonal thrombocytosis in triple-negative patients with isolated thrombocytosis based only on clinical or blood findings?
Tanja Belčič Mikič, Bor Vratanar, Tadej Pajič, Saša Anžej, Nataša Debeljak, Irena Preložnik-Zupan, Matjaž Sever, Samo Zver
Izvirni znanstveni članek
Oznake: klonska trombocitoza;esencialna trombocitemija;laktat dehidrogenaza;clonal thrombocytosis;essential thrombocythaemia;lactate dehydrogenase;
JAK2, MPL, and CALR mutations define clonal thrombocytosis in about 90% of patients with sustained isolated thrombocytosis. In the remainder of patients (triple-negative patients) diagnosing clonal thrombocytosis is especially difficult due to the different underlying conditions and possible inconcl ...
Leto: 2021 Vir: Medicinska fakulteta (UL MF)
Št. zadetkov: 4
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