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Št. zadetkov: 7
Presnova in signaliziranje lipidov v podganjih astrocitih v kulturi
Tina Smolič, Nina Vardjan
Doktorska disertacija
Oznake: astrociti;presnova lipidov;signaliziranje lipidov;lipidne kapljice;centralni živčni sistem;podgane;doktorske disertacije;
Astrociti so celice nevroglije v centralnem živčnem sistemu (CŽS) s številnimi funkcijami, med drugim skrbijo za presnovno homeostazo v CŽS in dostavljajo hranila (laktat, glukoza) nevronom. V patoloških stanjih CŽS astrociti kopičijo lipidne kapljice (LK), ki so skladišča prostih maščobnih kislin ( ...
Leto: 2021 Vir: Medicinska fakulteta (UL MF)
Vsebnost prehranske vlaknine v živilih rastlinskega izvora
Tina Smolič, Jasna Bertoncelj, Rajko Vidrih
Diplomsko delo
Oznake: živila rastlinskega izvora;zelenjava;kruh;sadje;prehranska vlaknina;topna prehranska vlaknina;netopna prehranska vlaknina;določanje vsebnosti prehranske vlaknine;energijska vrednost prehranske vlaknine;analizne metode;
Vsebnost prehranske vlaknine v živilih rastlinskega izvora
Leto: 2013 Vir: Biotehniška fakulteta (UL BF)
Pathophysiology of lipid droplets in neuroglia
Tina Smolič, Robert Zorec, Nina Vardjan, Nina Vardjan
Pregledni znanstveni članek
Oznake: nevroglija;astrociti;presnovni in oksidativni stres;neuroglia;astrocytes;metabolic and oxidative stress;
In recent years, increasing evidence regarding the functional importance of lipid droplets (LDs), cytoplasmic storage organelles in the central nervous system (CNS), has emerged. Although not abundantly present in the CNS under normal conditions in adulthood, LDs accumulate in the CNS during develop ...
Leto: 2022 Vir: Medicinska fakulteta (UL MF)
Ca[sup]2+ as the prime trigger of aerobic glycolysis in astrocytes
Anemari Horvat, Marko Muhič, Tina Smolič, Ena Begić, Robert Zorec, Marko Kreft, Nina Vardjan
Izvirni znanstveni članek
Oznake: astrocytes;aerobic glycolysis;d-glucose;
Astroglial aerobic glycolysis, a process during which d-glucose is converted to l-lactate, a brain fuel and signal, is regulated by the plasmalemmal receptors, including adrenergic receptors (ARs) and purinergic receptors (PRs), modulating intracellular Ca2+ and cAMP signals. However, the extent to ...
Leto: 2021 Vir: Medicinska fakulteta (UL MF)
Vpliv ekspresije gena familiarnega tipa Alzheimerjeve bolezni PS1[delta]E9 na mobilnost in sekrecijsko aktivnost astrocitov podgane v kulturi
Tina Smolič, Matjaž Stenovec, Matjaž Stenovec, Marko Kreft, Marko Kreft, Robert Zorec, Robert Zorec, Peter Maček
Magistrsko delo
Oznake: mobilnost mešičkov;astrociti;FAB;PS1[delta]E9;ANP;VGLUT1;kalcijeva signalizacija;
Vpliv ekspresije gena familiarnega tipa Alzheimerjeve bolezni PS1[delta]E9 na mobilnost in sekrecijsko aktivnost astrocitov podgane v kulturi
Leto: 2016 Vir: Biotehniška fakulteta (UL BF)
Astrocytes with TDP-43 inclusions exhibit reduced noradrenergic cAMP and Ca[sup]2+ signaling and dysregulated cell metabolism
Jelena Velebit Marković, Anemari Horvat, Tina Smolič, Sonja Prpar, Boris Rogelj, Robert Zorec, Nina Vardjan
Izvirni znanstveni članek
Oznake: astrociti;celična presnova;nevroni;astrocytes;cell metabolism;neurons;
Most cases of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) have cytoplasmic inclusions of TAR DNA-binding protein 43 (TDP-43) in neurons and non-neuronal cells, including astrocytes, which metabolically support neurons with nutrients. Neuronal metabolism largely depends on t ...
Leto: 2020 Vir: Medicinska fakulteta (UL MF)
Astrocytes in stress accumulate lipid droplets
Tina Smolič, Petra Tavčar Verdev, Anemari Horvat, Urška Černe, Ana Halužan Vasle, Larisa Tratnjek, Mateja Erdani-Kreft, Nicole Scholz, Maja Matis, Toni Petan, Robert Zorec, Nina Vardjan
Izvirni znanstveni članek
Oznake: astrocytes;stress stimuli;metabolism;
When the brain is in a pathological state, the content of lipid droplets (LDs), the lipid storage organelles, is increased, particularly in glial cells, but rarely in neurons. The biology and mechanisms leading to LD accumulation in astrocytes, glial cells with key homeostatic functions, are poorly ...
Leto: 2021 Vir: Medicinska fakulteta (UL MF)
Št. zadetkov: 7
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