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Št. zadetkov: 5
Izražanje genov za biosintezo likopena v kvasovki Yarrowia lipolytica
Patricija Prendl, Uroš Petrovič, Uroš Petrovič, Vasilka Magdevska, Vasilka Magdevska, Darja Žgur-Bertok, Darja Žgur-Bertok, Matej Butala
Magistrsko delo
Oznake: kvasovke;metabolni inženiring;metoda ʺGolden Gateʺ;produkcija likopena;
Terpeni so velika skupina organskih spojin, ki jih proizvajajo različni mikroorganizmi, rastline in tudi nekatere žuželke. Biosinteza poteka preko molekule izopentenil difosfat (IPP), ki je glavni gradnik za vse vrste terpenov. Terpeni se uporabljajo kot prehranska dopolnila v prehrani ljudi in živa ...
Leto: 2019 Vir: Biotehniška fakulteta (UL BF)
Vzpostavitev metodologije za vnos in izražanje heterolognega gena v glivi Trichoderma reesei RUT C30
Marija Zaharieva, Uroš Petrovič, Vasilka Magdevska
Magistrsko delo
Oznake: biotehnologija;glive;Trichoderma reesei;genski inženiring;metoda Gibson;
S pristopom genskega in metabolnega inženiringa lahko modificiramo naravni metabolizem organizma, da le-ta producira večjo količino želenega produkta ali da omogoča sintezo heterolognega metabolita. Filamentozne glive imajo pomembno vlogo v industrijski biotehnologiji. So privlačni organizmi za prod ...
Leto: 2022 Vir: Biotehniška fakulteta (UL BF)
Production of extracellular heterologous proteins in Streptomyces rimosus, producer of the antibiotic oxytetracycline
Andres Felipe Carrillo Rincon, Vasilka Magdevska, Luka Kranjc, Štefan Fujs, Rolf Müller, Hrvoje Petković
Izvirni znanstveni članek
Oznake: streptomicete;Streptomyces rimosus;sekundarni metaboliti;heterologni proteini;izražanje genov;encimi;fitaze;
Among the Streptomyces species, Streptomyces lividans has often been used for the production of heterologous proteins as it can secrete target proteins directly into the culture medium. Streptomyces rimosus, on the other hand, has for long been used at an industrial scale for oxytetracycline product ...
Leto: 2018 Vir: Biotehniška fakulteta (UL BF)
Integrated omics approaches provide strategies for rapid erythromycin yield increase in Saccharopolyspora erythraea
Katarina Karničar, Igor Drobnak, Marko Petek, Vasilka Magdevska, Jaka Horvat, Robert Vidmar, Špela Baebler, Ana Rotter, Polona Jamnik, Štefan Fujs, Boris Turk, Marko Fonović, Kristina Gruden, Gregor Kosec, Hrvoje Petković
Izvirni znanstveni članek
Oznake: aktinomicete;Saccharopolyspora erythraea;sekundarni metaboliti;antibiotiki;eritromicin;biosinteza;metabolno inženirstvo;proteomika;
Background Omics approaches have significantly increased our understanding of biological systems. However, they have had limited success in explaining the dramatically increased productivity of commercially important natural products by industrial high-producing strains, such as the erythromycin-pr ...
Leto: 2016 Vir: Nacionalni inštitut za biologijo (NIB)
SACE_5599, a putative regulatory protein, is involved in morphological differentiation and erythromycin production in Saccharopolyspora erythraea
Benjamin Kirm, Vasilka Magdevska, Miha Tome, Marinka Horvat, Katarina Karničar, Marko Petek, Robert Vidmar, Špela Baebler, Polona Jamnik, Štefan Fujs, Jaka Horvat, Marko Fonović, Boris Turk, Kristina Gruden, Hrvoje Petković, Gregor Kosec
Izvirni znanstveni članek
Oznake: aktinomicete;sekundarni metaboliti;eritromicin;regulacija biosinteze;molekularna genetika;erythromycin;polyketide;regulator;SACE_5599;lmbU;differentiation (biology);sporulation;strain improvement;metabolic engineering;
Background Erythromycin is a medically important antibiotic, biosynthesized by the actinomycete Saccharopolyspora erythraea. Genes encoding erythromycin biosynthesis are organized in a gene cluster, spanning over 60 kbp of DNA. Most often, gene clusters encoding biosynthesis of secondary metabolite ...
Leto: 2013 Vir: Repozitorij Univerze v Ljubljani (RUL)
Št. zadetkov: 5
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