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Št. zadetkov: 2
Cardiac stem cell aging and heart failure
Daniela Cesselli, Aneta Aleksova, Elisa Mazzega, Angela Caragnano, Antonio Paolo Beltrami
Pregledni znanstveni članek
Oznake: aging;heart failure;cardiomyocyte turnover;stem cells;cell senescence;cKit;Sca1;cardiospheres;
A side effect of the medical improvements of the last centuries is the progressive aging of the world population, which is estimated to reach the impressive number of 2 billion people with more than 65 years by 2050. As a consequence, age-related diseases, such as heart failure, will affect more and ...
Leto: 2018 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Ex vivo molecular rejuvenation improves the therapeutic activity of senescent human cardiac stem cells in a mouse model of myocardial infarction
Elisa Avolio, Giuseppe Gianfranceschi, Daniela Cesselli, Angela Caragnano, Emmanouil Athanasakis, Rajesh Katare, Marco Meloni, Anita Palma, Arianna Barchiesi, Carlo Vascotto, Elisa Mazzega
Izvirni znanstveni članek
Oznake: stem cells;myocardial infarction;heart failure;cellular senescence;
Cardiac stem cells (CSC) from explanted decompensated hearts (E-CSC) are, with respect to those obtained from healthy donors (D-CSC), senescent and functionally impaired. We aimed to identify alterations in signaling pathways that are associated with CSC senescence. Additionally, we inves- tigated i ...
Leto: 2014 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Št. zadetkov: 2
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