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Comparative study of interactions of aliskiren and AT [sub] 1 receptor antagonists with lipid bilayers
A. Sadegphour, Michael Rappolt, Dimitrios Ntountaniotis, Petros Chatzigeorgioug, Kyriakos Viras, Grigorios Megariotis, M. Papadopoulos, Eleni Siapi, Gregor Mali, Thomas Mavromoustakos
Izvirni znanstveni članek
Oznake: aliskiren;renin;PRR;DPPC bilayers;raman spectroscopy;solid state NMR spectroscopy;SAXS and WAXS;MD simulations;
The renin-angiotensin-aldosterone system (RAAS) plays a key role in the regulation of blood pressure. Renin is the rate limiting enzyme of the RAAS and aliskiren is a highly potent and selective inhibitor of the human renin. Renin is known to be active both in the circulating blood stream as well as ...
Leto: 2015 Vir: Kemijski inštitut (KI)
Št. zadetkov: 1
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