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Subchronic exposure of rats to sublethal dose of microcystin-YR induces DNA damage in multiple organs
Metka Filipič, Bojana Žegura, Bojan Sedmak, Irena Horvat-Žnidaršič, Aleksandra Milutinović Živin, Dušan Šuput
Izvirni znanstveni članek
Oznake: DNA damage;comet assay;cyanobacteria;bacterial toxins;rats;inbred F344;
Background. Microcystins (MCs) are cyclic heptapeptides that are considered tobe liver specific toxins. They are potent tumour promoters and recent studies indicate that they are also genotoxic. In this study we measured DNA damage in lymphocytes, liver, kidney (cortex and medulla), lung, spleen and ...
Leto: 2007 Vir: Nacionalni inštitut za biologijo (NIB)
Št. zadetkov: 1
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