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Electron paramagnetic resonance gives evidence for the presence of type 1 gonadotropin-releasing hormone receptor (GnRH-R) in subdomains of lipid rafts
Tilen Koklič, Alenka Hrovat, Ramon Guixà-González, Ismael Rodríguez-Espigares, Damaris Navio, Robert Frangež, Matjaž Uršič, Valentina Kubale, Ana Plemenitaš, Jana Selent, Marjeta Šentjurc, Milka Vrecl
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Oznake: 7TM receptors;type 1 gonadotropin-releasing hormone receptor;plasma membrane;electron paramagnetic resonance (EPR);lipid rafts;receptors;LHRH;cell membrane;electron spin resonance spectroscopy;
This study investigated the effect of type 1 gonadotropin releasing hormone receptor (GnRH-R) localization within lipid rafts on the properties of plasma membrane (PM) nanodomain structure. Confocal microscopy revealed colocalization of PM-localized GnRH-R with GM$_1$-enriched raft-like PM subdomain ...
Leto: 2021 Vir: Medicinska fakulteta (UL MF)
Št. zadetkov: 1
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