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Monocarbonyl curcumin analogues as potent inhibitors against human glutathione transferase P1-1
Panagiota Pantiora, Veronika Furlan, Dimitris Matiadis, Barbara Mavroidi, Fereniki Perperopoulou, Anastassios C. Papageorgiou, Marina Sagnou, Urban Bren, Maria Pelecanou, Nikolaos E. Labrou
Izvirni znanstveni članek
Oznake: glutathione transferase;enzyme inhibition;curcumin alalogues;
The isoenzyme of human glutathione transferase P1-1 (hGSTP1-1) is involved in multi-drug resistance (MDR) mechanisms in numerous cancer cell lines. In the present study, the inhibition potency of two curcuminoids and eleven monocarbonyl curcumin analogues against hGSTP1-1 was investigated. Demethoxy ...
Leto: 2023 Vir: Fakulteta za kemijo in kemijsko tehnologijo (UM FKKT)
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