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Sustained delivery of Cu(II)-based DNA intercalators by nanometer-sized cyclodextrin-based porous polymers
Tina Škorjanc, Julian Heinrich, Damjan Makuc, Nora Kulak, Matjaž Valant
Izvirni znanstveni članek
Oznake: porous organic polymers;cyclodextrin;DNA intercalators;Cu(II) complexes;metal complexes;
DNA intercalators are small molecules that insert between adjacent DNA base pairs and thus disturb DNA replication and transcription, which can lead to cell death. Certain metal complexes are excellent DNA intercalators, and have shown promise in chemotherapy. Here, a cyclodextrin porous polymer was ...
Leto: 2023 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
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