Št. zadetkov: 14
Pregledni znanstveni članek
Oznake:
apomorphine;Alzheimer’s disease;dopamine agonist;erectile dysfunction;Parkinson’s disease;impotence;pharmacology;drug therapy;diet therapy;
Apomorphine (APO) is an aporphine derivative used in human and veterinary medicine. APO activates D(1), D(2S), D(2L), D(3), D(4), and D(5) receptors (and is thus classified as a non-selective dopamine agonist), serotonin receptors (5HT(1A), 5HT(2A), 5HT(2B), and 5HT(2C)), and alpha-adrenergic recept ...
Leto:
2012
Vir:
Medicinska fakulteta (UL MF)
Pregledni znanstveni članek
Oznake:
Alzheimer's disease;amyloid [beta] oligomers;amyloid [beta] peptide;
Intracellular synthesis, folding, trafficking and degradation of proteins are controlled and integrated by proteostasis. The frequency of protein misfolding disorders in the human population, e.g., in Alzheimer's disease (AD), is increasing due to the aging population. AD treatment options are limit ...
Leto:
2018
Vir:
Medicinska fakulteta (UL MF)
Pregledni znanstveni članek
Oznake:
nanotechnology;nano particles;Alzheimer’s disease;memory impairment;animal models;
Currently, there is no cure for Alzheimer’s disease (AD) in humans; treatment is symptomatic only. Aging of the population, together with an unhealthy diet and lifestyle, contribute to the steady, global increase of AD patients. This increase creates significant health, societal and economical chall ...
Leto:
2021
Vir:
Medicinska fakulteta (UL MF)
Pregledni znanstveni članek
Oznake:
Alzheimer’s disease;memory impairment;animal models;human studies;ageing;neuroinflammation;physical exercise;
This narrative review summarises the evidence for considering physical exercise (PE) as a non-pharmacological intervention for delaying cognitive decline in patients with Alzheimer’s disease (AD) not only by improving cardiovascular fitness but also by attenuating neuroinflammation. Ageing is the mo ...
Leto:
2022
Vir:
Medicinska fakulteta (UL MF)
Izvirni znanstveni članek
Oznake:
capillary supply;fluorescence imaging;nerve injury;
Recently, we evaluated capillary indices without discrimination by fiber type in rat extensor digitorum longus muscle (EDL) 4 weeks after nerve cut (NC), after double nerve crush (double NCR) and in two controls, from the start (CON-1) and the end (CON-2) of the experiment. In the present study, we ...
Leto:
2019
Vir:
Medicinska fakulteta (UL MF)
Izvirni znanstveni članek
Oznake:
poškodba živca;kapilarnost;fluorescentno slikanje;nerve injury;capillarity;fluorescence imaging;
We have previously shown by 3D study that 2 weeks after nerve injury there was no change in the length of capillaries per muscle fibre length in rat extensor digitorum longus muscle (EDL). The primary goal of the present 2D study was to determine the capillarity of rat EDL 4 weeks after various mode ...
Leto:
2016
Vir:
Medicinska fakulteta (UL MF)
Izvirni znanstveni članek
Oznake:
histokemija;imunofluorescenčni madeži;vrste mišičnih vlaken;histochemistry;immunofluorescent staining;muscle fiber types;
We developed a staining protocol that enables simultaneous visualization of myosin heavy chain (MHC) pure and hybrid muscle fiber types in rat skeletal muscle. Up to eight differ-ent muscle fiber types can be visualized in a single section of the rat extensor digitorum longus muscle, which contains ...
Leto:
2013
Vir:
Medicinska fakulteta (UL MF)
Pregledni znanstveni članek
Oznake:
consciousness;cognitive binding;general anaesthesia monitors;soft sensors;general anaesthesia;
One of the current challenges in medicine is monitoring the patients’ depth of general anaesthesia (DGA). Accurate assessment of the depth of anaesthesia contributes to tailoring drug administration to the individual patient, thus preventing awareness or excessive anaesthetic depth and improving pat ...
Leto:
2010
Vir:
Medicinska fakulteta (UL MF)
Diplomsko delo
Oznake:
Yii;spletno orodje;slapovni model;življenjski model razvoja informacijskih sistemov;primeri uporabe;PHP;aplet Java;računalništvo;univerzitetni študij;diplomske naloge;
Razvoj spletne aplikacije e-Asistent z uporabno spletnega orodja Yii
Leto:
2013
Vir:
Fakulteta za računalništvo in informatiko (UL FRI)
Pregledni znanstveni članek
Oznake:
Alzheimer's disease;;autophagy;Parkinson's disease;
Proteostasis are integrated biological pathways within cells that control synthesis, folding, trafficking and degradation of proteins. The absence of cell division makes brain proteostasis susceptible to age-related changes and neurodegeneration. Two key processes involved in sustaining normal brain ...
Leto:
2015
Vir:
Medicinska fakulteta (UL MF)