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Št. zadetkov: 6
Morphological and immunocytochemical characterization of tumor spheroids in ascites from high-grade serous carcinoma
Simona Miceska, Erik Škof, Gorana Gašljević, Veronika Kloboves-Prevodnik
Izvirni znanstveni članek
Oznake: maligne celice;visokomaligni rak;rak jajčnikov;cell blocks;high-grade serous carcinoma;ovarian carcinoma;
Tumor spheroids in the ascites of high-grade serous carcinoma (HGSC) are poorly described. Our objective was to describe their morphological features, cellular composition, PD-1 and PD-L1 expression, and survival correlation of these parameters. The density and size of spheroids were assessed in Gie ...
Leto: 2023 Vir: Medicinska fakulteta (UM MF)
Morfološke značilnosti cirkulirajočih tumorskih celic raka dojk v krvi po izolaciji na podlagi njihovih fizikalnih ali bioloških lastnosti
Simona Miceska, Tanja Dolinšek, Živa Modic, Cvetka Grašič-Kuhar, Maja Čemažar, Urška Matkovič, Jerneja Varl, Anamarija Kuhar, Veronika Kloboves-Prevodnik
Objavljeni povzetek znanstvenega prispevka na konferenci
Oznake: citologija;diagnostika;onkologija;
Leto: 2022 Vir: Onkološki inštitut Ljubljana (OI)
Potentiation of electrochemotherapy effectiveness by immunostimulation with IL-12 gene electrotransfer in mice is dependent on tumor immune status
Katja Uršič, Špela Kos, Urška Kamenšek, Maja Čemažar, Simona Miceska, Boštjan Markelc, Simon Buček, Barbara Starešinič, Veronika Kloboves-Prevodnik, Richard Heller, Gregor Serša
Izvirni znanstveni članek
Oznake: elektrokemoterapija;elektroprenos genov;interlevkin-12;electrochemotherapy;gene electrotransfer;interleukin-12;
Electrochemotherapy (ECT) exhibits high therapeutic effectiveness in the clinic, achieving up to 80% local tumor control but without a systemic (abscopal) effect. Therefore, we designed a combination therapy consisting of ECT via intratumoral application of bleomycin, oxaliplatin or cisplatin with p ...
Leto: 2021 Vir: Onkološki inštitut Ljubljana (OI)
Nižje število cirkulirajočih tumorskih celic v poznih linijah razsejanega raka dojk
Silvester Jernej, Klara Geršak, Marina Mencinger, Tanja Ovčariček, Tanja Dolinšek, Živa Modic, Simona Miceska, Maja Čemažar, Veronika Kloboves-Prevodnik, Cvetka Grašič-Kuhar
Objavljeni povzetek strokovnega prispevka na konferenci
Oznake: onkologija;rak dojke;kemoterapija;
Leto: 2022 Vir: Onkološki inštitut Ljubljana (OI)
Association of circulating tumor cells, megakaryocytes and a high immune-inflammatory environment in metastatic breast cancer
Cvetka Grašič-Kuhar, Silvester Jernej, Marina Mencinger, Tanja Ovčariček, Maja Čemažar, Simona Miceska, Živa Modic, Anamarija Kuhar, Tanja Dolinšek, Veronika Kloboves-Prevodnik
Izvirni znanstveni članek
Oznake: rak dojke;kroženje tumorskih celic;preživetje;breast cancer;circulating tumor cell;overall survival;
Liquid biopsy is becoming an important source of new biomarkers during the treatment of metastatic cancer patients. Using size-based microfluid technology, we isolated circulating tumor cells (CTCs) from metastatic breast cancer patients to evaluate their presence and cluster formation, as well as t ...
Leto: 2023 Vir: Medicinska fakulteta (UM MF)
ǂThe ǂprognostic and predictive value of human gastrointestinal microbiome and exosomal mRNA expression of PD-L1 and IFNγ for immune checkpoint inhibitors response in metastatic melanoma patients
Ana Erman, Marija Ignjatović, Katja Leskovšek, Simona Miceska, Urša Lampreht Tratar, Maša Bošnjak, Veronika Kloboves-Prevodnik, Maja Čemažar, Lidija Kandolf Sekulović, Gorazd Avguštin, Janja Ocvirk, Tanja Mesti
Izvirni znanstveni članek
Oznake: gastrointestinalni mikrobiom;mRNA;imunski kontrolni zaviralci;metastatski melanom;gastrointestinal microbiome;mRNA expression of PD-L1 and IFNγ;immune checkpoint inhibitors;metastatic melanoma;
Background: Immunotherapy has been successful in treating advanced melanoma, but a large proportion of patients do not respond to the treatment with immune checkpoint inhibitors (ICIs). Preclinical and small cohort studies suggest gastrointestinal microbiome composition and exosomal mRNA expression ...
Leto: 2023 Vir: Onkološki inštitut Ljubljana (OI)
Št. zadetkov: 6
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