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ǂA ǂputative serine protease is required to initiate the RIPK3-MLKL-mediated necroptotic death pathway in neutrophils
Xiaoliang Wang, Damjan Avsec, Aleš Obreza, Shida Yousefi, Irena Mlinarič-Raščan, Hans-Uwe Simon
Izvirni znanstveni članek
Oznake: necroptosis;neutrophil;serine protease;signal transduction;small molecule inhibitor;
Adhesion receptors, such as CD44, have been shown to activate receptor interacting protein kinase-3 (RIPK3)-mixed lineage kinase-like (MLKL) signaling, leading to a non-apoptotic cell death in human granulocyte/macrophage colony-stimulating factor (GM-CSF) - primed neutrophils. The signaling events ...
Leto: 2021 Vir: Fakulteta za farmacijo (UL FFA)
Št. zadetkov: 1
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