Jezik: | Slovenski jezik |
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Leto izida: | 2023 |
Tipologija: | 2.11 - Diplomsko delo |
Organizacija: | UL FKKT - Fakulteta za kemijo in kemijsko tehnologijo |
Založnik: | [I. Ostojić] |
UDK: | 547.78.057(043.2) |
COBISS: | 165430275 |
Št. ogledov: | 49 |
Št. prenosov: | 13 |
Ocena: | 0 (0 glasov) |
Metapodatki: |
Sekundarni jezik: | Angleški jezik |
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Sekundarni naslov: | Synthesis of some 2-aryl-1,2-dihydro-3H-pyrazol-3-ones |
Sekundarni povzetek: | Since their discovery, pyrazolones have become very important for industry, science, and health because of their wide range of utility and easy synthesis. One of their numer-ous effects is antibacterial. A major problem of modern times is the bacterial resistance to antibiotics. For this reason, we decided to synthesize a series of pyrazol-3-ones and test their inhibitory effect on bacterial growth. By varying the substituents at positions 2 and 5, we tested the influence of different groups on the effectiveness of pyrazolones. The syntheses were performed by simple condensation of the corresponding hydrazines and ß-keto esters under mild conditions. The products were purified by column chroma-tography or trituration and the antibacterial effect of the synthesized compounds on 4 bacterial strains was tested by the disk diffusion method. |
Sekundarne ključne besede: | synthesis;pyrazolones;bacterial growth inhibition;Organska sinteza (kemija);Pirazoli;Univerzitetna in visokošolska dela; |
Vrsta dela (COBISS): | Diplomsko delo/naloga |
Študijski program: | 1000373 |
Konec prepovedi (OpenAIRE): | 1970-01-01 |
Komentar na gradivo: | Univ. v Ljubljani, Fak. za kemijo in kemijsko tehnologijo, UNI Kemija |
Strani: | 37 str. |
ID: | 19888192 |