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Fine tuning of cholinesterase and glutathione-S-transferase activities by organoruthenium(II) complexes
Tomaž Trobec, Kristina Sepčić, Monika C. Žužek, Jerneja Kladnik, Nina Podjed, Catarina Cardoso Páscoa, Iztok Turel, Robert Frangež
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Oznake: cholinesterase;enzyme inhibition;glutathione S-transferase;organoruthenium complex;pyrithione;β-diketone;carbonyl;glutathione transferase;
Cholinesterases (ChEs) show increased activities in patients with Alzheimer’s disease, and remain one of the main therapeutic targets for treatment of this neurodegenerative disorder. A library of organoruthenium(II) complexes was prepared to investigate the influence of their structural elements on ...
Leto: 2021 Vir: Veterinarska fakulteta (UL VF)
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