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Št. zadetkov: 3
Ostreolysin A/pleurotolysin B and equinatoxins
Robert Frangež, Dušan Šuput, Jordi Molgó, Evelyne Benoit
Pregledni znanstveni članek
Oznake: ostreolysin A/pleurotolysin B;equinatoxins;pore-forming proteins;biological effects;pore forming cytotoxic proteins;relative biological effectiveness;
Acidic ostreolysin A/pleurotolysin B (OlyA/PlyB, formerly known as ostreolysin (Oly), and basic 20 kDa equinatoxins (EqTs) are cytolytic proteins isolated from the edible mushroom Pleurotus ostreatus and the sea anemone Actinia equina, respectively. Both toxins, although from different sources, shar ...
Leto: 2017 Vir: Veterinarska fakulteta (UL VF)
Structural and functional characterization of an organometallic ruthenium complex as a potential myorelaxant drug
Tomaž Trobec, Monika C. Žužek, Kristina Sepčić, Jerneja Kladnik, Jakob Kljun, Iztok Turel, Evelyne Benoit, Robert Frangež
Izvirni znanstveni članek
Oznake: organoruthenium nitrophenanthroline complex;acetylcholinesterase;butyrylcholinesterase;glutathione S-transferase;mouse neuromuscular system;ruthenium;muscle relaxation;physiology;glutathione transferase;
In addition to antibacterial and antitumor effects, synthetic ruthenium complexes have been reported to inhibit several medicinally important enzymes, including acetylcholinesterase (AChE). They may also interact with muscle-type nicotinic acetylcholine receptors (nAChRs) and thus affect the neuromu ...
Leto: 2020 Vir: Veterinarska fakulteta (UL VF)
New insights into the effects of organometallic ruthenium complexes on nicotinic acetylcholine receptors
Tomaž Trobec, Nicolas Lamassiaude, Evelyne Benoit, Monika C. Žužek, Kristina Sepčić, Jerneja Kladnik, Iztok Turel, Rómulo Aráoz, Robert Frangež, Robert Frangež
Izvirni znanstveni članek
Oznake: organometallic ruthenium complexes;nicotinic acetylcholine receptors;nicotinic antagonists;electrophysiology;two-electrode voltage-clamp technique;
Nicotinic acetylcholine receptors (nAChRs) are expressed in excitable and non-excitable cells of the organism. Extensive studies suggest that nAChR ligands have therapeutic potential, notably for neurological and psychiatric disorders. Organometallic ruthenium complexes are known to inhibit several ...
Leto: 2024 Vir: Veterinarska fakulteta (UL VF)
Št. zadetkov: 3
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