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Using virtual AChE homology screening to identify small molecules with the ability to inhibit marine biofouling
Homayon John Arabshahi, Tomaž Trobec, Valentin Foulon, Claire Hellio, Robert Frangež, Kristina Sepčić, Patrick Cahill, Johan Svenson
Izvirni znanstveni članek
Oznake: homology screening;in silico screening;in vitro enzymatic studies;cholinesterase;AChE inhibitor;antifouling;
The search for effective yet environmentally friendly strategies to prevent marine biofouling is hampered by the large taxonomic diversity amongst fouling organisms and a lack of well-defined conserved molecular targets. The acetylcholinesterase enzyme catalyses the breakdown of the neurotransmit ...
Leto: 2021 Vir: Veterinarska fakulteta (UL VF)
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