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Št. zadetkov: 11
SwitCCh
Jana Aupič, Fabio Lapenta, Roman Jerala
Izvirni znanstveni članek
Oznake: načrtovanje proteinov;ovite vijačnice;metaloproteini;konformacijska stikala;
SwitCCh : metal-site design for controlling the assembly of a coiled-coil homodimer
Leto: 2018 Vir: Kemijski inštitut (KI)
Towards designing new nano-scale protein architectures
Jana Aupič, Fabio Lapenta, Žiga Strmšek, Roman Jerala
Izvirni znanstveni članek
Oznake: biokemija;struktura snovi;proteini;
Towards designing new nano-scale protein architectures
Leto: 2016 Vir: Kemijski inštitut (KI)
Oligomeric self-assembly of a coiled-coil-based bipyramidal protein cage
Fabio Lapenta, Jana Aupič, Žiga Strmšek, Roman Jerala
Objavljeni povzetek znanstvenega prispevka na konferenci
Oznake: protein design;coiled coils;CCPO;
Oligomeric self-assembly of a coiled-coil-based bipyramidal protein cage
Leto: 2021 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
ǂThe ǂconformational plasticity of the selectivity filter methionines controls the in-cell Cu(I) uptake through the CTR1 transporter
Pavel Janoš, Jana Aupič, Sharon Ruthstein, Alessandra Magistrato
Izvirni znanstveni članek
Oznake: Copper;membrane transporter;molecular dynamics;QM/MM;free energy;
Copper is a trace element vital to many cellular functions. Yet its abnormal levels are toxic to cells, provoking a variety of severe diseases. The high affinity copper transporter 1 (CTR1), being the main in-cell copper [Cu(I)] entry route, tightly regulates its cellular uptake via a still elusive ...
Leto: 2022 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Intrinsically disordered ectodomain modulates ion permeation through a metal transporter
Jana Aupič, Fabio Lapenta, Pavel Janoš, Alessandra Magistrato
Izvirni znanstveni članek
Oznake: ion channels and transporters;intrinsically disordered regions;molecular dynamics;function regulation;
Intrinsically disordered ectodomain modulates ion permeation through a metal transporter
Leto: 2022 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Triangular in vivo self-assembling coiled-coil protein origami
Sabina Božič, Helena Gradišar, Jana Aupič, Adam Round, Roman Jerala
Izvirni znanstveni članek
Oznake: coiled coil;enzyme clustering;biosynthesis;resveratrol;mevalonate;
Triangular in vivo self-assembling coiled-coil protein origami
Leto: 2021 Vir: Kemijski inštitut (KI)
Načrtovanje de novo proteinskega konformacijskega stikala na osnovi motiva ovite vijačnice
Jana Aupič, Roman Jerala, Jurij Lah, Kristina Djinović Carugo, Gregor Anderluh
Doktorska disertacija
Oznake: proteini;načrtovanje proteinov;motiv ovite vijačnice;proteinska zvitja;konformacijska stikala;molekulsko modeliranje;doktorske disertacije;
Narava je tekom evolucije uporabila le del konformacijskega prostora, ki je na voljo polipeptidnim molekulam. Z načrtovanjem sintetičnih proteinov je mogoče ta nepreizkušen prostor načrtno preiskati in v njem odkriti popolnoma nova proteinska zvitja z novimi, v naravi neopaženimi lastnostmi ...
Leto: 2020 Vir: Fakulteta za kemijo in kemijsko tehnologijo (UL FKKT)
Designed folding pathway of modular coiled-coil-based proteins
Jana Aupič, Žiga Strmšek, Fabio Lapenta, David Pahovnik, Tomaž Pisanski, Igor Drobnak, Ajasja Ljubetič, Roman Jerala
Izvirni znanstveni članek
Oznake:
Designed folding pathway of modular coiled-coil-based proteins
Leto: 2021 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Dynamical interplay between the human high-affinity copper transporter hCtr1 and its cognate metal ion
Gulshan Walke, Jana Aupič, Hadeel Kashoua, Pavel Janoš, Shelly Meron, Yulia Shenberger, Zena Qasem, Lada Gevorkyan-Airapetov, Alessandra Magistrato, Sharon Ruthstein
Izvirni znanstveni članek
Oznake: Ctr1;copper;EPR;molecular dynamics;
Abnormal cellular copper levels have been clearly implicated in genetic diseases, cancer, and neurodegeneration. Ctr1, a high-affinity copper transporter, is a homotrimeric integral membrane protein that provides the main route for cellular copper uptake. Together with a sophisticated copper transpo ...
Leto: 2022 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Self-assembly and regulation of protein cages from pre-organised coiled-coil modules
Fabio Lapenta, Jana Aupič, Marco Vezzoli, Žiga Strmšek, Stefano Da Vela, Dmitrii Ivanovich Svergun, José María Carazo, Roberto Melero, Roman Jerala
Izvirni znanstveni članek
Oznake: self-assembly;regulation;protein cages;pre-organised coiled-coil modules;
Self-assembly and regulation of protein cages frompre-organised coiled-coil modules
Leto: 2021 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Št. zadetkov: 11
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